Equity (Tables)

3 Months Ended

Mar. 31, 2022

Stockholders' Equity Note [Abstract]

Share-based Payment Arrangement, Expensed and Capitalized, Amount

Share-based compensation expense was recorded in the following financial statement line items:

	Three Months Ended March 31,
	2022		2021
Cost of product sales	$	1.7	$	1.5
Cost of contract development and manufacturing	0.4		0.2
Research and development	1.1		1.4
Selling, general and administrative	6.7		7.4
Total share-based compensation expense	$	9.9	$	10.5

Schedule of Accumulated Other Comprehensive Income (Loss)

The following table includes changes in accumulated other comprehensive income (loss), net of tax by component:

	Defined Benefit Pension Plan		Derivative Instruments		Foreign Currency Translation Losses		Total
(in millions, net of tax)
Balance, December 31, 2021	$	(4.0)	$	(4.5)	$	(7.6)	$	(16.1)
Other comprehensive (loss) income before reclassifications	—		4.9		0.5		5.4
Amounts reclassified from accumulated other comprehensive income	—		1.4		—		1.4
Net current period other comprehensive income (loss)	—		6.3		0.5		6.8
Balance, March 31, 2022	$	(4.0)	$	1.8	$	(7.1)	$	(9.3)
Balance, December 31, 2020	$	(7.7)	$	(11.0)	$	(6.6)	$	(25.3)
Other comprehensive (loss) income before reclassifications	—		1.7		(2.2)		(0.5)
Amounts reclassified from accumulated other comprehensive income	—		1.4		—		1.4
Net current period other comprehensive income (loss)	—		3.1		(2.2)		0.9
Balance, March 31, 2021	$	(7.7)	$	(7.9)	$	(8.8)	$	(24.4)

Comprehensive Income (Loss)

The following table presents the tax effects related to each component of accumulated other comprehensive (loss) income:

	March 31, 2022						March 31, 2021
	Pretax		Tax Benefit (Expense)		Net of tax		Pretax		Tax Benefit (Expense)		Net of tax
Derivative Instruments	$	8.6	$	(2.3)	$	6.3	$	2.4	$	0.7	$	3.1
Foreign Currency Translation Losses	0.7		(0.2)		0.5		(2.2)		—		(2.2)
Total Adjustments	$	9.3	$	(2.5)	$	6.8	$	0.2	$	0.7	$	0.9