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Consolidated Statements of Cash Flows - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Cash flows from operating activities:      
Net income $ 230.9 $ 305.1 $ 54.5
Adjustments to reconcile net income to net cash provided by operating activities:      
Stock-based compensation expense 42.4 51.0 26.7
Depreciation and amortization 123.8 114.5 110.7
Change in fair value of contingent obligations, net 2.9 31.7 24.8
Amortization of deferred financing costs 4.1 3.5 3.0
Impairments 41.7 29.0 12.0
Deferred income taxes 46.9 (2.4) (1.1)
Write off of contract asset and liability (17.2) 0.0 0.0
Other 2.0 (5.2) (0.2)
Changes in operating assets and liabilities:      
Accounts receivable (48.2) 49.0 (8.2)
Inventories (44.0) (83.2) (16.7)
Prepaid expenses and other assets (24.7) (29.2) (39.1)
Accounts payable (2.5) 19.8 16.5
Accrued expenses and other liabilities (9.2) 19.4 (15.1)
Accrued compensation 4.0 21.8 4.2
Contract liabilities (31.8) 11.2 16.0
Net cash provided by operating activities 321.1 536.0 188.0
Cash flows from investing activities:      
Purchases of property, plant and equipment (225.0) (141.0) (86.9)
Milestone payment from prior asset acquisition 0.0 (10.0) (10.0)
Net cash used in investing activities (225.0) (151.0) (96.9)
Cash flows (used in) provided by financing activities:      
Purchases of treasury stock (106.0) 0.0 0.0
Proceeds from revolving credit facility 0.0 0.0 130.0
Proceeds from senior unsecured notes 0.0 450.0 0.0
Principal payments on convertible senior notes (10.6) 0.0 0.0
Principal payments on revolving credit facility 0.0 (373.0) (105.0)
Principal payments on term loan facility (25.3) (14.1) (11.3)
Proceeds from stock-based compensation activity 15.9 31.6 8.2
Taxes paid for stock-based compensation activity (13.8) (13.8) (7.4)
Debt issuance costs 0.0 (8.4) 0.0
Contingent consideration payments (1.2) (2.8) (50.4)
Net cash (used in) provided by financing activities: (141.0) 69.5 (35.9)
Effect of exchange rate changes on cash, cash equivalents and restricted cash (0.3) (1.0) 0.4
Net change in cash, cash equivalents and restricted cash (45.2) 453.5 55.6
Cash, cash equivalents and restricted cash at beginning of period 621.5 168.0 112.4
Cash, cash equivalents and restricted cash at end of period 576.3 621.5 168.0
Supplemental disclosure of cash flow information:      
Cash paid during the year for interest 30.4 21.0 34.5
Cash paid during the year for income taxes 71.6 109.3 30.8
Supplemental information on non-cash investing and financing activities:      
Purchases of property, plant and equipment unpaid at period end 20.0 22.0 12.3
Purchases of treasury stock 6.6 0.0 0.0
Reconciliation of cash and cash equivalents and restricted cash:      
Cash and cash equivalents 576.1 621.3 167.8
Restricted cash 0.2 0.2 0.2
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total $ 576.3 $ 621.5 $ 168.0