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Intangible assets and goodwill (Tables)
 12 Months Ended
Dec. 31, 2021
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of Finite-Lived Intangible Assets
The Company's intangible assets consist of products acquired via business combinations or asset acquisitions. Components of the Company’s intangible assets, excluding IPR&D and goodwill, consisted of the following:
December 31, 2021
(in millions) 
Estimated Life
Cost
Accumulated Amortization
Net
Products
9-22 years
$798.0 $193.5 $604.5 
Customer relationships8 years28.6 28.6 — 
CDMO8 years5.5 5.4 0.1 
    Total intangible assets$832.1 $227.5 $604.6 
December 31, 2020
(in millions) 
Estimated Life
Cost
Accumulated Amortization
Net
Products
9-22 years
$798.0 $137.8 $660.2 
Customer relationships8 years28.6 26.5 2.1 
CDMO8 years5.5 4.7 0.8 
    Total intangible assets$832.1 $169.0 $663.1 
Summary of Future Amortization Expense
Future amortization expense as of December 31, 2021 is as follows:
(in millions)
 
2022$55.9 
202355.8 
202455.8 
202555.8 
2026 and beyond381.3 
Total remaining amortization$604.6 
Summary of Goodwill
The following table is a summary of changes in goodwill:
 
Year ended December 31,
(in millions) 
20212020
Balance at beginning of the year$266.7 $266.6 
Goodwill impairment (1)(41.7)— 
Foreign currency translation(0.1)0.1 
Balance at end of the year$224.9 $266.7 
(1) The carrying amount of goodwill included accumulated impairments of $41.7 million as of December 31, 2021. There were no impairment charges or accumulated impairments as of December 31, 2020.