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Stock-based compensation (Tables)
 6 Months Ended
Jun. 30, 2020
Stockholders' Equity Note [Abstract]  
Share-based Payment Arrangement, Expensed and Capitalized, Amount
Stock-based compensation expense was recorded in the following financial statement line items:
 
Three Months Ended June 30,
 
Six Months Ended June 30,
 
2020
 
2019
 
2020
 
2019
Cost of product sales and contract development and manufacturing services
$
8.1

 
$
0.6

 
$
8.8

 
$
1.4

Research and development
5.4

 
1.0

 
6.3

 
2.1

Selling, general and administrative
10.9

 
6.5

 
15.9

 
11.4

Total stock-based compensation expense
$
24.4

 
$
8.1

 
$
31.0

 
$
14.9