Condensed Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019
Revenues:
Total revenues	$ 192.5	$ 190.6
Operating expenses:
Cost of product sales and contract development and manufacturing services	76.9	91.8
Research and development	42.7	46.1
Selling, general and administrative	69.7	65.4
Amortization of intangible assets	14.8	14.5
Total operating expenses	204.1	217.8
Loss from operations	(11.6)	(27.2)
Other (expense) income:
Interest expense	(8.6)	(9.6)
Other expense, net	(1.1)	(1.0)
Total other expense, net	(9.7)	(10.6)
Loss before provision for income taxes	(21.3)	(37.8)
Income tax benefit	8.8	11.8
Net loss	$ (12.5)	$ (26.0)
Net loss per common share
Basic (in dollars per share)	$ (0.24)	$ (0.51)
Diluted (in dollars per share)	$ (0.24)	$ (0.51)
Shares used in computing loss per share
Basic (in shares)	52.0	51.2
Diluted (in shares)	52.0	51.2
Product sales, net
Revenues:
Total revenues	$ 148.2	$ 153.0
Contract development and manufacturing services
Revenues:
Total revenues	21.7	15.9
Contracts and grants
Revenues:
Total revenues	$ 22.6	$ 21.7