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Acquisitions - PaxVax Narrative (Details) $ in Millions		3 Months Ended
Acquisitions - PaxVax Narrative (Details) $ in Millions	Oct. 04, 2018 USD ($) employee	Mar. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)
Business Acquisition [Line Items]
Weighted average amortization period		14 years 3 months 18 days
Goodwill		$ 267.7	$ 259.7
PaxVax
Business Acquisition [Line Items]
Number of employees \| employee	250
Total purchase price	$ 273.1
Acquired intangible asset	$ 133.0
Weighted average amortization period	19 years
Acquired in-process research and development	$ 0.0
Goodwill	$ 70.6
Vivotif \| PaxVax
Business Acquisition [Line Items]
Present value, discount rate	14.50%
Vaxchora \| PaxVax
Business Acquisition [Line Items]
Present value, discount rate	15.00%