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Condensed Consolidated Statements of Operations - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Revenues:    
Total revenues $ 190.6 $ 117.8
Operating expenses:    
Cost of product sales and contract manufacturing 91.8 54.3
Research and development 46.1 29.1
Selling, general and administrative 65.4 40.0
Amortization of intangible assets 14.5 3.9
Total operating expenses 217.8 127.3
Loss from operations (27.2) (9.5)
Other income (expense):    
Interest expense (9.6) (0.2)
Other income (expense), net (1.0) 0.3
Total other income (expense), net (10.6) 0.1
Loss before benefit from income taxes (37.8) (9.4)
Income tax benefit (11.8) (4.5)
Net loss $ (26.0) $ (4.9)
Net loss per common share    
Basic (in dollars per share) $ (0.51) $ (0.10)
Diluted (in dollars per share) $ (0.51) $ (0.10)
Shares used in computing loss per share    
Basic (in shares) 51,224,125 49,580,089
Diluted (in shares) 51,224,125 49,580,089
Product sales, net    
Revenues:    
Total revenues $ 153.0 $ 75.8
Contract manufacturing    
Revenues:    
Total revenues 15.9 26.1
Contracts and grants    
Revenues:    
Total revenues $ 21.7 $ 15.9