Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions		12 Months Ended
		Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Revenues:
Total revenues		$ 782.4	$ 560.9	$ 488.8
Operating expenses:
Cost of product sales and contract manufacturing		322.3	187.7	126.3
Research and development		142.8	97.4	106.9
Selling, general and administrative		202.5	142.9	143.1
Amortization of intangible assets		25.0	8.6	7.0
Total operating expenses		692.6	436.6	383.3
Income from operations		89.8	124.3	105.5
Other income (expense):
Interest expense		(9.9)	(6.6)	(7.6)
Other income (expense), net		1.6	0.9	1.3
Total other income (expense), net		(8.3)	(5.7)	(6.3)
Income before provision for income taxes		81.5	118.6	99.2
Provision for income taxes		18.8	36.0	36.7
Net Income from continuing operations		62.7	82.6	62.5
Net loss from discontinued operations		0.0	0.0	(10.7)
Net income		$ 62.7	$ 82.6	$ 51.8
Net income (loss) per share - basic:
Net income per share from continuing operations-basic (in dollars per share)		$ 1.25	$ 1.98	$ 1.56
Net loss per share from discontinued operations-basic (in dollars per share)		0	0	(0.27)
Net income per share-basic (in dollars per share)		1.25	1.98	1.29
Net income (loss) per share - diluted:
Net income from continuing operations-diluted (in dollars per share)		1.22	1.71	1.35
Net loss per share from discontinued operations-diluted (in dollars per share)		0	0	(0.22)
Net income per share-diluted (in dollars per share)	[1]	$ 1.22	$ 1.71	$ 1.13
Weighted-average number of shares - basic (in shares)		50.1	41.8	40.2
Weighted-average number of shares - diluted (in shares)		51.4	50.3	49.3
Product Sales [Member]
Revenues:
Total revenues		$ 606.5	$ 421.5	$ 296.3
Contract Manufacturing [Member]
Revenues:
Total revenues		98.9	68.9	49.1
Contracts and Grants [Member]
Revenues:
Total revenues		$ 77.0	$ 70.5	$ 143.4

[1] See "Earnings per share" footnote for details on calculation.