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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Cash flows from operating activities:    
Net income $ 66,181 $ 48,652
Adjustments to reconcile to net cash provided by (used in) operating activities:    
Stock-based compensation expense 16,664 11,805
Depreciation and amortization 37,106 29,899
Income taxes 12,761 18,618
Change in fair value of contingent obligations 1,917 1,350
Other 1,515 703
Changes in operating assets and liabilities:    
Accounts receivable 66,455 9,411
Inventories 17,067 5,113
Income taxes (10,130) (5,515)
Prepaid expenses and other assets (5,921) (2,157)
Accounts payable (5,695) 2,965
Accrued expenses and other liabilities 2,457 (2,334)
Accrued compensation 3,925 (1,902)
Deferred revenue 3,262 14,006
Net cash provided by operating activities 207,564 130,614
Cash flows from investing activities:    
Purchases of property, plant and equipment and other (51,275) (42,381)
Proceeds from sale of assets 2,624 0
Net cash used in investing activities (48,651) (42,381)
Cash flows from financing activities:    
Issuance of common stock upon exercise of stock options 11,402 10,799
Debt issuance costs 0 (1,426)
Taxes paid on behalf of employees for equity activity (6,303) (4,184)
Payments of notes payable to Aptevo 0 (20,000)
Contingent consideration payments (2,234) (2,744)
Restricted cash 0 (1,043)
Purchase of treasury stock (145) (83)
Net cash provided by (used in) financing activities 2,720 (18,681)
Effect of exchange rate changes on cash, cash equivalents and restricted cash (567) (74)
Net increase in cash, cash equivalents and restricted cash 161,066 69,478
Cash, cash equivalents and restricted cash at beginning of period 179,335 [1] 271,513
Cash, cash equivalents and restricted cash at end of period $ 340,401 [1] $ 340,991
[1] As of December 31, 2017 and September 30, 2018, the balance includes $1,043 of restricted cash.