Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands		3 Months Ended
		Mar. 31, 2018	Mar. 31, 2017
Revenues:
Product sales		$ 75,771	$ 81,969
Contract manufacturing		26,178	17,628
Contracts and grants		15,865	17,261
Total revenues		117,814	116,858
Operating expenses:
Cost of product sales and contract manufacturing		58,044	46,322
Research and development		29,051	20,476
Selling, general and administrative		40,204	35,150
Income (loss) from operations		(9,485)	14,910
Other income (expense):
Interest income		222	373
Interest expense		(234)	(1,938)
Other income, net		74	300
Total other income (expense), net		62	(1,265)
Income (loss) before provision for income taxes		(9,423)	13,645
Provision for (benefit from) income taxes		(4,515)	3,160
Net income (loss)		$ (4,908)	$ 10,485
Net income (loss) per share - basic:
Net income (loss) per share - basic (in dollars per share)		$ (0.10)	$ 0.26
Net income (loss) per share - diluted:
Net income (loss) per share - diluted (in dollars per share)	[1]	$ (0.10)	$ 0.23
Weighted-average number of shares - basic (in shares)		49,580,089	40,727,755
Weighted-average number of shares - diluted (in shares)		49,580,089	49,718,426

[1] See "Earnings per share" footnote for details on calculation.