Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands	3 Months Ended				9 Months Ended
	Sep. 30, 2017		Sep. 30, 2016		Sep. 30, 2017	Sep. 30, 2016
Revenues:
Product sales	$ 114,296		$ 96,698		$ 259,875	$ 208,785
Contract manufacturing	18,912		14,712		52,700	32,455
Contracts and grants	16,226		31,504		54,489	95,879
Total revenues	149,434		142,914		367,064	337,119
Operating expenses:
Cost of product sales and contract manufacturing	44,503		39,560		125,449	93,025
Research and development	22,659		27,188		68,886	81,173
Selling, general and administrative	34,503		40,688		101,521	108,328
Income from operations	47,769		35,478		71,208	54,593
Other income (expense):
Interest income	637		358		1,593	764
Interest expense	(1,991)		(2,049)		(5,734)	(5,082)
Other expense, net	(101)		(234)		(387)	(176)
Total other expense, net	(1,455)		(1,925)		(4,528)	(4,494)
Income from continuing operations before provision for income taxes	46,314		33,553		66,680	50,099
Provision for income taxes	12,763		13,165		18,028	19,861
Net Income from continuing operations	33,551		20,388		48,652	30,238
Net income (loss) from discontinued operations	0		952		0	(15,854)
Net income	$ 33,551		$ 21,340		$ 48,652	$ 14,384
Net income (loss) per share - basic:
Net income per share from continuing operations-basic (in dollars per share)	$ 0.81		$ 0.50		$ 1.19	$ 0.75
Net income (loss) per share from discontinued operations-basic (in dollars per share)	0		0.02		0	(0.40)
Net income per share - basic (in dollars per share)	0.81		0.52		1.19	0.35
Net income (loss) per share - diluted:
Net income from continuing operations - diluted (in dollars per share)	0.68	[1]	0.43	[1]	1.03	0.68
Net income (loss) per share from discontinued operations-diluted (in dollars per share)	0		0.02		0	(0.32)
Net income per share - diluted (in dollars per share)	$ 0.68	[1]	$ 0.45	[1]	$ 1.03	$ 0.36
Weighted-average number of shares - basic (in shares)	41,222,504		40,465,423		40,989,813	40,071,730
Weighted-average number of shares - diluted (in shares)	50,467,829		49,440,313		50,090,088	48,826,597

[1] See "Earnings per share" for details on calculation.