Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands	3 Months Ended				6 Months Ended
	Jun. 30, 2017		Jun. 30, 2016		Jun. 30, 2017	Jun. 30, 2016
Revenues:
Product sales	$ 63,610		$ 48,333		$ 145,579	$ 112,087
Contract manufacturing	16,160		10,156		33,788	17,743
Contracts and grants	21,002		32,752		38,263	64,375
Total revenues	100,772		91,241		217,630	194,205
Operating expenses:
Cost of product sales and contract manufacturing	34,624		29,465		80,946	53,466
Research and development	25,751		27,893		46,227	53,985
Selling, general and administrative	31,868		35,925		67,018	67,639
Income (loss) from operations	8,529		(2,042)		23,439	19,115
Other income (expense):
Interest income	583		219		956	406
Interest expense	(1,805)		(1,510)		(3,743)	(3,033)
Other income (expense), net	(586)		24		(286)	57
Total other expense, net	(1,808)		(1,267)		(3,073)	(2,570)
Income (loss) from continuing operations before provision for (benefit from) income taxes	6,721		(3,309)		20,366	16,545
Provision for (benefit from) income taxes	2,105		(1,267)		5,265	6,698
Net Income (loss) from continuing operations	4,616		(2,042)		15,101	9,847
Net Loss from discontinued operations	0		(8,905)		0	(16,803)
Net income (loss)	$ 4,616		$ (10,947)		$ 15,101	$ (6,956)
Net income (loss) per share - basic:
Net income (loss) per share from continuing operations-basic (in dollars per share)	$ 0.11		$ (0.05)		$ 0.37	$ 0.25
Net loss per share from discontinued operations-basic (in dollars per share)	0		(0.22)		0	(0.42)
Net income per share - basic (in dollars per share)	0.11		(0.27)		0.37	(0.17)
Net income (loss) per share - diluted:
Net income (loss) from continuing operations - diluted (in dollars per share)	0.11	[1]	(0.05)	[1]	0.35	0.24
Net loss per share from discontinued operations-diluted (in dollars per share)	0		(0.22)		0	(0.34)
Net income (loss) per share - diluted (in dollars per share)	$ 0.11	[1]	$ (0.27)	[1]	$ 0.35	$ (0.10)
Weighted-average number of shares - basic (in shares)	41,013,764		40,202,821		40,871,540	39,872,738
Weighted-average number of shares - diluted (in shares)	50,078,594		40,202,821		49,899,291	48,784,339

[1] See "Earnings per share" for details on calculation.