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MorphoSys collaboration agreement (Details)
12 Months Ended
Dec. 31, 2015
USD ($)
Unit
Dec. 31, 2014
USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Short-term deferred revenue $ 7,942,000 $ 5,345,000
Long-term deferred revenue 6,590,000 5,713,000
Morphosys [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Non refundable receipt 20,000,000  
First contingent payment received based upon development and regulatory milestones $ 5,000,000  
Tiered royalty obligation 20.00%  
Number of units of accounting | Unit 2  
Proceeds allocated to two units of accounting $ 20,000,000  
Proceeds allocated to license 15,300,000  
Proceeds allocated to development services $ 4,700,000  
Present value factor for estimating selling price of license 12.00%  
Revenue from license fee $ 15,300,000  
Reduction to research and development expense 4,262,000 1,509,000
Accounts receivable 0.5 1.0
Short-term deferred revenue 700,000 900,000
Long-term deferred revenue 3,200,000 $ 3,500,000
Morphosys Amended Agreement [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
First contingent payment received based upon development and regulatory milestones 32,500,000  
Second contingent payment received based upon development and regulatory milestones 41,500,000  
Funding requirement cap 460,000,000  
Morphosys Original Agreement [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Additional contingent payment that may be received 163,000,000  
First contingent payment received based upon development and regulatory milestones 80,000,000  
Second contingent payment received based upon development and regulatory milestones $ 83,000,000  
Collaborative agreement, rights and obligations 0.36  
Funding requirement cap $ 186,000,000  
Morphosys Amended-2016 [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Collaborative agreement, rights and obligations 0.75  
Morphosys Amended 2017-2018 [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Collaborative agreement, rights and obligations 0.49  
Morphosys Amended 2019 and Beyond [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Collaborative agreement, rights and obligations 0.36