Segment information (Tables)

12 Months Ended

Dec. 31, 2015

Segment information [Abstract]

Segment information

	Reportable Segments
(in thousands)	Biodefense			Biosciences			All Other			Total
Year Ended December 31, 2015
External revenue	$	450,088		$	72,701		$	-		$	522,789
Intersegment revenue (expense)		(1,877	)		1,877			-			-
Research and development		111,663			37,816			4,518			153,997
Interest income		149			-			423			572
Interest expense		-			(41	)		(6,482	)		(6,523	)
Depreciation and amortization		18,677			5,597			227			24,501
Net income (loss)		125,609			(55,644	)		(7,095	)		62,870
Intangible assets		34,770			22,605			-			57,375
In-process research and development assets		701			41,800			-			42,501
Goodwill		34,264			20,638			-			54,902
Total assets		511,875			345,995			185,722			1,043,592
Expenditures for long-lived assets		37,735			6,689			388			44,812
Year Ended December 31, 2014
External revenue	$	370,547		$	79,591		$	-		$	450,138
Intersegment revenue (expense)		-			-			-			-
Research and development		81,975			60,821			8,033			150,829
Interest income		62			-			258			320
Interest expense		-			-			(8,240	)		(8,240	)
Depreciation and amortization		17,669			5,070			267			23,006
Net income (loss)		96,966			(51,300	)		(8,925	)		36,741
Intangible assets		40,979			17,365			-			58,344
In-process research and development assets		10,528			50,100			-			60,628
Goodwill		31,239			21,346			-			52,585
Total assets		433,226			344,420			161,045			938,691
Expenditures for long-lived assets		26,736			2,444			1,493			30,673
Year Ended December 31, 2013
External revenue	$	311,564		$	1,181		$	-		$	312,745
Intersegment revenue (expense)		-			-			-			-
Research and development		62,663			50,652			6,618			119,933
Interest income		-			-			139			139
Interest expense		-			-			-			-
Depreciation and amortization		15,584			1,238			186			17,008
Net income (loss)		87,289			(50,925	)		(5,229	)		31,135
Intangible assets		30,148			0			0			30,148
In-process research and development assets		-			41,800			-			41,800
Goodwill		8,452			5,502			-			13,954
Total assets		331,827			98,510			196,293			626,630
Expenditures for long-lived assets		30,700			1,343			9,978			42,021