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Consolidated Statements of Cash Flows (Unaudited) (USD $)
In Thousands, unless otherwise specified
9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Cash flows from operating activities:    
Net income (loss) $ 3,141 $ (10,787)
Adjustments to reconcile to net cash provided by (used in) operating activities:    
Stock-based compensation expense 8,417 7,911
Depreciation and amortization 7,679 6,926
Deferred income taxes 8,679 11,937
Non-cash development expenses from joint ventures 3,163 4,263
Change in fair value of contingent value rights (3,005) 1,325
Impairment of in-process research and development 9,600 0
Impairment of long-lived assets 0 676
Excess tax benefits from stock-based compensation 1,485 (1,502)
Other (39) 60
Changes in operating assets and liabilities:    
Accounts receivable 57,006 (9,705)
Inventories (3,584) (5,257)
Income taxes (1,597) (15,760)
Prepaid expenses and other assets (1,544) 132
Accounts payable (3,495) (278)
Accrued expenses and other liabilities 301 (194)
Accrued compensation (4,790) (9,350)
Deferred revenue 212 (5,143)
Net cash provided by (used in) operating activities 81,629 (24,746)
Cash flows from investing activities:    
Purchases of property, plant and equipment (40,943) (34,153)
Proceeds from sale of assets 11,765 0
Proceeds from maturity of investments 1,966 3,750
Purchase of investments 0 (5,220)
Net cash used in investing activities (27,212) (35,623)
Cash flows from financing activities:    
Proceeds from borrowings on long-term indebtedness 12,946 21,298
Issuance of common stock subject to exercise of stock options 495 8,836
Excess tax benefits from stock-based compensation (1,485) 1,502
Principal payments on long-term indebtedness (9,386) (14,931)
Contingent value right payment (1,748) 0
Purchase of treasury stock (1,457) 0
Release of restricted cash deposit 220 0
Net cash provided by (used in) financing activities (415) 16,705
Effect of exchange rate changes on cash and cash equivalents (2) (9)
Net increase (decrease) in cash and cash equivalents 54,000 (43,673)
Cash and cash equivalents at beginning of period 143,901 169,019
Cash and cash equivalents at end of period $ 197,901 $ 125,346