LIMITED POWER OF ATTORNEY

OF

SV LIFE SCIENCES FUND IV, L.P.



	This statement confirms that the undersigned has authorized and designated each
of Suzanne Hamel and Thomas B. Rosedale his attorneys-in-fact to (i) prepare, execute
and file on behalf of the undersigned Form ID or any other necessary documents or forms
in order to obtain access codes (including, without limitation, CIK and CCC codes) for
the undersigned to permit filing on EDGAR, and (ii) prepare, execute and file on behalf
of the undersigned all Forms 3, 4 and 5 (including any amendments thereto) that the
undersigned may be required to file with the U.S. Securities and Exchange Commission
as a result of the undersigned's ownership of or transactions in securities of a public
reporting company or by virtue of the undersigned holding board of director or executive
officer positions with a public reporting company.  The authority of such attorneys under
this Power of Attorney shall continue until the undersigned is no longer required to file
Forms 3, 4 and 5 with the U.S. Securities and Exchange Commission, unless earlier
revoked in writing.  The undersigned acknowledges that such attorneys are not assuming
any of the undersigned's responsibilities to comply with the requirements of Section 16 of
the Securities Exchange Act of 1934, as amended, or any of the undersigned's liabilities
for failure to comply with such requirements.



					SV LIFE SCIENCES FUND IV, L.P.

					By: SV Life Sciences Fund IV (GP), L.P.,
					its Sole General Partner
					By: SVLSF IV, LLC, its sole General
					Partner



Date: August 22, 2013	 		  _/s/ Denise W. Marks_________________
						  Name: Denise W. Marks
						  Title: Member