EX-16.1 15 f21666a3exv16w1.htm EXHIBIT 16.1 exv16w1

Exhibit 16.1
PriceWaterhouseCoopers Letterhead
November 30, 2006
Securities and Exchange Commission
100 F Street, N.E.
Washington, DC 20549
We have read the statements made by Oculus Innovative Sciences, Inc. (copy attached), which we understand will be filed with the Securities and Exchange Commission, as part of the Form S-1 (Amendment No. 3) of Oculus Innovative Sciences, Inc. under the heading “Change in Independent Registered Public Accounting Firm”. We agree with the statements concerning our Firm in such Form S-1 (Amendment No. 3). However, we make no comment on the current status of remedial actions taken with respect to reportable events disclosed in such Form S-1 (Amendment No. 3).
Very truly yours,
/s/ PricewaterhouseCoopers LLP
PricewaterhouseCoopers LLP