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Stockholders' Equity - Warrant (Details) - USD ($)
12 Months Ended
Jun. 19, 2017
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Jul. 25, 2017
Jun. 30, 2017
Jun. 29, 2017
Class of Warrant or Right [Line Items]              
Common stock, par value (in dollars per share)   $ 0.0001 $ 0.0001     $ 0.0001  
Common stock, shares issued (in shares)   27,707,328 23,102,728        
Series A-1 warrant liability $ 3,300,000 $ 3,313,000 $ 0 $ 0      
Change in fair value of warrant liability   (2,217,000) 0 $ 0      
Aggregate intrinsic value of the warrant   0          
Series A Preferred Stock              
Class of Warrant or Right [Line Items]              
Value of shares redeemed   $ 13,800,000 $ 2,800,000        
Number of shares redeemed (in shares)   83,502 18,498        
Reduction in the original recorded value of preferred stock   $ 8,400,000 $ 1,800,000        
Reduction in the accretive value of the preferred stock   $ 5,400,000 $ 1,000,000        
Common Stock Warrant              
Class of Warrant or Right [Line Items]              
Common stock, par value (in dollars per share)   $ 0.0001          
Right to acquire variable amount of common stock, term 15 months            
Common Stock Warrant | Soryn HLDR              
Class of Warrant or Right [Line Items]              
Exercise price (in dollars per share) $ 3.18 $ 3.18          
Term of warrant 3 years 2 years 6 months          
Common Stock | Common Stock Warrant | Soryn HLDR              
Class of Warrant or Right [Line Items]              
Common stock warrant purchased (in shares) 2,355,506         2,400,000 2,000,000
Common stock, shares issued (in shares) 2,000,000       46,370 309,136  
Series A-1 warrant liability   $ 1,100,000          
Change in fair value of warrant liability   $ 2,200,000