SEC FORM 4

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Melo John

(Last)

(First)

(Middle)

C/O AMYRIS, INC.

5885 HOLLIS ST., SUITE 100

(Street)

EMERYVILLE

94608

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
AMYRIS, INC. [ AMRS ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	President and CEO

3. Date of Earliest Transaction (Month/Day/Year)
10/10/2011

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	10/10/2011		M⁽¹⁾		20,000	A	$0.28	20,000	I⁽²⁾	John and Mary Melo Family Foundation⁽²⁾
Common Stock	10/10/2011		S⁽¹⁾		20,000⁽³⁾	D	$17.216⁽⁴⁾	0	I⁽²⁾	John and Mary Melo Family Foundation⁽²⁾
Common Stock								23,000	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Stock Option (Right to Buy)	$0.28	10/10/2011		M⁽¹⁾			20,000	⁽⁵⁾⁽⁶⁾	01/18/2017	Common Stock	20,000	$0	40,000	I⁽⁷⁾	John and Mary Melo Family Foundation⁽²⁾
Stock Option (Right to Buy)	$0.28							⁽⁵⁾⁽⁶⁾	01/18/2017	Common Stock	553,730		553,730	D
Stock Option (Right to Buy)	$0.28							⁽⁵⁾⁽⁶⁾	01/18/2017	Common Stock	18,539		18,539	I⁽⁸⁾	Melo Family 2010 Distribution Trust⁽⁸⁾
Stock Option (Right to Buy)	$0.28							⁽⁵⁾⁽⁶⁾	01/18/2017	Common Stock	9,936		9,936	I⁽⁹⁾	Descendant's Trust #1⁽⁹⁾
Stock Option (Right to Buy)	$0.28							⁽⁵⁾⁽⁶⁾	01/18/2017	Common Stock	9,936		9,936	I⁽¹⁰⁾	Descendant's Trust #2⁽¹⁰⁾
Stock Option (Right to Buy)	$0.28							⁽⁵⁾⁽⁶⁾	01/18/2017	Common Stock	9,936		9,936	I⁽¹¹⁾	Descendant's Trust #3⁽¹¹⁾
Stock Option (Right to Buy)	$0.28							⁽⁵⁾⁽⁶⁾	01/18/2017	Common Stock	26,653		26,653	I⁽¹²⁾	Melo Renewal Trust⁽¹²⁾

Explanation of Responses:

1. ***RULE 10B5-1 TRADING PLAN TRANSACTION: EACH OF THE FOREGOING OPTION EXERCISE AND STOCK SALES WAS EFFECTED PURSUANT TO A RULE 10B5-1 TRADING PLAN ADOPTED BY THE JOHN AND MARY MELO FAMILY FOUNDATION ON SEPTEMBER 9, 2011.***

2. The shares are directly beneficially held by the John and Mary Melo Family Foundation (the "Foundation"). Mr. Melo is the President of the Foundation and, as such, has voting and/or investment power over the securities held by the Foundation.

3. Represents the aggregate of sales effected on the same day at different prices pursuant to the plan in footnote (1).

4. Represents the weighted average sales price per share. The shares sold at prices ranging from $16.66 to $17.55 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

5. Immediately exercisable.

6. The stock option vested as to 1/5th of the total number of shares subject to the option on October 23, 2007, and thereafter vested and shall vest as to 1/60th of the total number of shares subject to the option in equal monthly installments.

7. This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on September 1, 2011 to the Foundation.

8. This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on March 18, 2010 to the Melo Family 2010 Distribution Trust.

9. This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on April 4, 2011 to the Descendant's Trust #1.

10. This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on April 4, 2011 to the Descendant's Trust #2.

11. This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on April 4, 2011 to the Descendant's Trust #3.

12. This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on April 4, 2011 to the Melo Renewal Trust.

Remarks:

	/s/ John Melo by Nicholas Khadder, Attorney-in-Fact	10/12/2011
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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