As filed with the Securities and Exchange Commission on October 18, 2012

SECURITIES ACT FILE NO. 333-135105

INVESTMENT COMPANY ACT FILE NO. 811-21910

=========================================================================================================================================================================================================================================

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM N-1A

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 x

Pre-Effective Amendment No. ¨

Post Effective Amendment No. 125 x

and/or

REGISTRATION STATEMENT UNDER THE INVESTMENT COMPANY ACT OF 1940 x

Amendment No. 127

(Check appropriate box or boxes)

CLAYMORE EXCHANGE-TRADED FUND TRUST 2

(EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)

2455 CORPORATE WEST DRIVE

LISLE, ILLINOIS 60532

(Address of Principal Executive Offices)

(630) 505-3700

Registrant's Telephone Number

KEVIN M. ROBINSON, ESQ.

GUGGENHEIM FUNDS INVESTMENT ADVISORS, LLC

2455 CORPORATE WEST DRIVE

LISLE, ILLINOIS 60532

(Name and Address of Agent for Service)

Copy to:

STUART M. STRAUSS, ESQ.

DECHERT LLP

1095 AVENUE OF THE AMERICAS

NEW YORK, NY 10036

APPROXIMATE DATE OF PROPOSED PUBLIC OFFERING:

IT IS PROPOSED THAT THIS FILING WILL BECOME EFFECTIVE (CHECK APPROPRIATE BOX)

x            IMMEDIATELY UPON FILING PURSUANT TO PARAGRAPH (B) OF RULE 485.

¨            ON [DATE] PURSUANT TO PARAGRAPH (B) OF RULE 485.

¨            60 DAYS AFTER FILING PURSUANT TO PARAGRAPH (A)(1) OF RULE 485.

¨            ON [DATE] PURSUANT TO PARAGRAPH (A) OF RULE 485.

¨            75 DAYS AFTER FILING PURSUANT TO PARAGRAPH (A)(2) OF RULE 485.

¨            ON [DATE] PURSUANT TO PARAGRAPH (A)(2) OF RULE 485.

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EXPLANATORY NOTE

This filing relates to the following series of the Registrant:

Guggenheim Canadian Energy Income ETF

Guggenheim China Real Estate ETF

Guggenheim China Small Cap ETF

Guggenheim Frontier Markets ETF

Guggenheim International Multi-Asset Income ETF

Guggenheim Shipping ETF

Guggenheim Timber ETF

Guggenheim Yuan Bond ETF

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SIGNATURES

Pursuant to the requirements of the Securities Act of 1933 and the Investment Company Act of 1940, the Registrant certifies that it meets all the requirements for effectiveness pursuant to Rule 485(b) under the Securities Act of 1933 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Lisle and State of Illinois on the 18th day of October, 2012.

CLAYMORE EXCHANGE-TRADED FUND TRUST 2

By:              /s/ Donald C. Cacciapaglia

Donald C. Cacciapaglia

Chief Executive Officer

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed below by the following persons in the capacities and on the date indicated.

SIGNATURES	TITLE	DATE
*
Randall C. Barnes	Trustee	October 18, 2012
*
Roman Friedrich III	Trustee	October 18, 2012
*
Robert B. Karn III	Trustee	October 18, 2012
*
Ronald A. Nyberg	Trustee	October 18, 2012
*
Ronald E. Toupin, Jr.	Trustee	October 18, 2012
/s/ Donald C. Cacciapaglia Donald C. Cacciapaglia	Trustee and Chief Executive Officer	October 18, 2012
/s/ John L. Sullivan John L. Sullivan	Treasurer, Chief Financial Officer and Chief Accounting Officer	October 18, 2012
/s/ Kevin M. Robinson		October 18, 2012
Kevin M. Robinson *Attorney-In-Fact, pursuant to power of attorney

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EXHIBIT INDEX

EX-101.INS	XBRL Instance Document
EX-101.SCH	XBRL Taxonomy Extension Schema Document
EX-101.CAL	XBRL Taxonomy Extension Calculation Linkbase
EX-101.DEF	XBRL Taxonomy Extension Definition Linkbase
EX-101.LAB	XBRL Taxonomy Extension Labels Linkbase
EX-101.PRE	XBRL Taxonomy Extension Presentation Linkbase

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