Note 8 - Related Party Transactions (Details)	3 Months Ended	9 Months Ended							9 Months Ended	1 Months Ended	3 Months Ended		9 Months Ended
	Sep. 30, 2013 Guarantee of Indebtedness of Others [Member] USD ($)	Sep. 30, 2013 Guarantee of Indebtedness of Others [Member] USD ($)	Sep. 30, 2013 Numab Agreement [Member] Restricted Cash [Member] USD ($)	Sep. 30, 2013 Numab Agreement [Member] Zurcher Kantonalbank [Member] CHF	Sep. 30, 2013 Numab Agreement [Member] USD ($)	Sep. 30, 2013 Numab Agreement [Member] CHF	Sep. 30, 2011 Numab Agreement [Member] Maximum [Member] USD ($)	Sep. 30, 2011 Numab Agreement [Member] Maximum [Member] CHF	Sep. 30, 2013 R-Tech [Member] Ueno Fine Chemical [Member]	Oct. 31, 2012 R-Tech [Member] USD ($)	Sep. 30, 2013 R-Tech [Member] USD ($)	Sep. 30, 2012 R-Tech [Member] USD ($)	Sep. 30, 2013 R-Tech [Member] USD ($)	Sep. 30, 2012 R-Tech [Member] USD ($)	Jun. 30, 2013 R-Tech [Member] USD ($)	Mar. 31, 2013 R-Tech [Member] USD ($)
Note 8 - Related Party Transactions (Details) [Line Items]
Contracts Revenue											$ 105,000	$ 112,000	$ 373,000	$ 321,000
Manufacture and Supply Period of Inactivity of Certain Product										18 months
Purchase Commitment, Remaining Minimum Amount Committed										5,600,000
SignificantPurchaseCommitmentSatisfiedAmount															5,600,000	5,600,000
Lease Term									30 years
Remaining Lease Term									20 years
Loans Pledged as Collateral (in Francs)			2,400,000	2,200,000	2,400,000	2,200,000	5,000,000	5,000,000
Loans Pledged as Collateral			2,400,000	2,200,000	2,400,000	2,200,000	5,000,000	5,000,000
Loans Pledged as Collateral, Amount Deposited (in Francs)						2,200,000
Debt Instrument, Face Amount (in Francs)						2,000,000
Loss Contingency Accrual, Provision	$ 153,000	$ 512,000