Condensed Consolidated Statements of Operations and Comprehensive Income (Loss) (Unaudited) (USD $) Share data in Thousands, except Per Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2013	Sep. 30, 2012	Sep. 30, 2013	Sep. 30, 2012
Revenues:
Research and development revenue	$ 2,027,000	$ 737,000	$ 16,288,000	$ 6,418,000
Product royalty revenue	13,595,000	13,890,000	37,271,000	36,521,000
Product sales revenue	5,378,000		10,994,000
Co-promotion revenue		730,000	61,000	3,253,000
Contract and collaboration revenue	163,000	139,000	490,000	433,000
Total revenues	21,163,000	15,496,000	65,104,000	46,625,000
Cost of goods sold	6,267,000		9,457,000
Gross profit	14,896,000	15,496,000	55,647,000	46,625,000
Operating expenses:
Research and development	4,474,000	5,615,000	14,528,000	14,202,000
General and administrative	5,440,000	7,256,000	18,635,000	22,598,000
Selling and marketing	6,026,000	4,278,000	15,967,000	14,474,000
Total operating expenses	15,940,000	17,149,000	49,130,000	51,274,000
Income (loss) from operations	(1,044,000)	(1,653,000)	6,517,000	(4,649,000)
Non-operating income (expense):
Interest income	20,000	68,000	63,000	118,000
Interest expense	(461,000)	(596,000)	(1,449,000)	(1,780,000)
Other income (expense), net	(49,000)	8,000	1,776,000	727,000
Total non-operating income (expense), net	(490,000)	(520,000)	390,000	(935,000)
Income (loss) before income taxes	(1,534,000)	(2,173,000)	6,907,000	(5,584,000)
Income tax benefit (provision)	2,825,000	(3,776,000)	(2,641,000)	(3,112,000)
Net income (loss)	1,291,000	(5,949,000)	4,266,000	(8,696,000)
Net income (loss) per share:
Basic net income (loss) per share (in Dollars per share)	$ 0.03	$ (0.14)	$ 0.10	$ (0.21)
Diluted net income (loss) per share (in Dollars per share)	$ 0.03	$ (0.14)	$ 0.10	$ (0.21)
Weighted average common shares outstanding - basic (in Shares)	41,863	41,678	41,644	41,697
Weighted average common shares outstanding - diluted (in Shares)	42,787	41,678	42,662	41,697
Net income (loss)	1,291,000	(5,949,000)	4,266,000	(8,696,000)
Other comprehensive income (loss):
Unrealized gain (loss) on investments, net of tax effect	18,000	28,000	(16,000)	23,000
Foreign currency translation	(253,000)	(175,000)	(387,000)	(1,767,000)
Comprehensive income (loss)	$ 1,056,000	$ (6,096,000)	$ 3,863,000	$ (10,440,000)