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Note 14 - Segment Reporting
9 Months Ended
Sep. 30, 2013
Segment Reporting [Abstract]  
Segment Reporting Disclosure [Text Block]
14.           Segment Reporting

The Company has determined that it has three reportable segments based on the Company’s method of internal reporting, which disaggregates business by geographic location. These segments are the Americas, Europe and Asia. The Company evaluates the performance of these segments based on income (loss) from operations, as well as other factors, that depend on the development status of these geographies. Such measures include the progress of its research and development activities, collaboration and licensing efforts, commercialization activities, product sales and other factors. The reportable segments have historically derived their revenue from joint collaboration and strategic alliance agreements. Transactions between the segments consist primarily of loans and the provision of research and development services. The following tables summarize the financial information by reportable geographic segment for the three and nine months ended September 30, 2013 and 2012:

(In thousands)
 
Americas
   
Europe
   
Asia
   
Consolidated
 
Three Months Ended September 30, 2013
                       
Research and development revenue
  $ 2,027     $ -     $ -     $ 2,027  
Product royalty revenue
    13,595       -       -       13,595  
Product sales revenue
    170       17       5,191       5,378  
Co-promotion revenue
    -       -       -       -  
Contract and collaboration revenue
    141       12       10       163  
Total revenues
    15,933       29       5,201       21,163  
Cost of goods sold
    3,389       4       2,874       6,267  
Gross profit
    12,544       25       2,327       14,896  
Research and development expenses
    2,467       1,088       919       4,474  
Depreciation and amortization
    309       47       8       364  
Other operating expenses
    8,893       1,646       563       11,102  
Income (loss) from operations
    875       (2,756 )     837       (1,044 )
Interest income
    18       2       -       20  
Interest expense
    -       (417 )     (44 )     (461 )
Other non-operating expense, net
    6       95       (150 )     (49 )
Income (loss) before income taxes
  $ 899     $ (3,076 )   $ 643     $ (1,534 )
Capital expenditures
  $ 9     $ 4     $ -     $ 13  
                                 
Three Months Ended September 30, 2012
                               
Research and development revenue
  $ 665     $ 72     $ -     $ 737  
Product royalty revenue
    13,890       -       -       13,890  
Product sales revenue
    -       -       -       -  
Co-promotion revenue
    730       -       -       730  
Contract and collaboration revenue
    141       (15 )     13       139  
Total revenues
    15,426       57       13       15,496  
Cost of goods sold
    -       -       -       -  
Gross profit
    15,426       57       13       15,496  
Research and development expenses
    2,239       2,543       833       5,615  
Depreciation and amortization
    122       242       10       374  
Other operating expenses
    9,677       1,161       322       11,160  
Income (loss) from operations
    3,388       (3,889 )     (1,152 )     (1,653 )
Interest income
    65       3       -       68  
Interest expense
    -       (556 )     (40 )     (596 )
Other non-operating expense, net
    34       165       (191 )     8  
Income (loss) before income taxes
  $ 3,487     $ (4,277 )   $ (1,383 )   $ (2,173 )
Capital expenditures
  $ 41     $ -     $ -     $ 41  
                                 

(In thousands)
 
Americas
   
Europe
   
Asia
   
Consolidated
 
Nine Months Ended September 30, 2013
                       
Research and development revenue
  $ 16,288     $ -     $ -     $ 16,288  
Product royalty revenue
    37,271       -       -       37,271  
Product sales revenue
    277       37       10,680       10,994  
Co-promotion revenue
    61       -       -       61  
Contract and collaboration revenue
    424       34       32       490  
Total revenues
    54,321       71       10,712       65,104  
Cost of goods sold
    3,465       12       5,980       9,457  
Gross profit
    50,856       59       4,732       55,647  
Research and development expenses
    6,446       4,307       3,775       14,528  
Depreciation and amortization
    543       548       26       1,117  
Other operating expenses
    27,368       3,374       2,743       33,485  
Income (loss) from operations
    16,499       (8,170 )     (1,812 )     6,517  
Interest income
    54       8       1       63  
Interest expense
    -       (1,326 )     (123 )     (1,449 )
Other non-operating expense, net
    (9 )     (169 )     1,954       1,776  
Income (loss) before income taxes
  $ 16,544     $ (9,657 )   $ 20     $ 6,907  
Capital expenditures
  $ 40     $ 110     $ 3     $ 153  
                                 
Nine Months Ended September 30, 2012
                               
Research and development revenue
  $ 5,878     $ 74     $ 466     $ 6,418  
Product royalty revenue
    36,521       -       -       36,521  
Product sales revenue
    -       -       -       -  
Co-promotion revenue
    3,253       -       -       3,253  
Contract and collaboration revenue
    424       (30 )     39       433  
Total revenues
    46,076       44       505       46,625  
Cost of goods sold
    -       -       -       -  
Gross profit
    46,076       44       505       46,625  
Research and development expenses
    6,250       5,405       2,547       14,202  
Depreciation and amortization
    366       709       30       1,105  
Other operating expenses
    32,475       2,576       916       35,967  
Income (loss) from operations
    6,985       (8,646 )     (2,988 )     (4,649 )
Interest income
    105       12       1       118  
Interest expense
    -       (1,656 )     (124 )     (1,780 )
Other non-operating expense, net
    67       82       578       727  
Income (loss) before income taxes
  $ 7,157     $ (10,208 )   $ (2,533 )   $ (5,584 )
Capital expenditures
  $ 293     $ 3,445     $ -     $ 3,738  
                                 

As of September 30, 2013
                       
Property and equipment, net
  $ 975     $ 121     $ 182     $ 1,278  
Identifiable assets, net of intercompany loans
                               
and investments
  $ 97,915     $ 13,420     $ 18,385     $ 129,720  
                                 
As of December 31, 2012
                               
Property and equipment, net
  $ 1,276     $ 36     $ 228     $ 1,540  
Identifiable assets, net of intercompany loans
                               
and investments
  $ 87,731     $ 25,465     $ 14,600     $ 127,796