NPORT-P false 0001364608 XXXXXXXX S000075528 C000234707 First Trust Exchange-Traded Fund II 811-21944 0001364608 549300HY3NFBU00W8S30 120 East Liberty Drive Suite 400 Wheaton 60187 630-765-8000 First Trust Nasdaq Lux Digital Health Solutions ETF S000075528 549300D67CSMMN7O4494 2022-09-30 2022-06-30 N 1465816.79 790.47 1465026.32 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 N Globus Medical Inc 5299003M2P4CIK0RF205 379577208 596.00000000 NS USD 33459.44000000 2.283879787224 Long EC CORP US N 1 N N N Progyny Inc N/A 74340E103 374.00000000 NS USD 10864.70000000 0.741604423871 Long EC CORP US N 1 N N N Axonics Inc 549300LJY4X7N57VJL05 05465P101 244.00000000 NS USD 13827.48000000 0.943838333225 Long EC CORP US N 1 N N N Sema4 Holdings Corp N/A 81663L101 948.00000000 NS USD 1194.48000000 0.081533006178 Long EC CORP US N 1 N N N Inspire Medical Systems Inc 549300XQQCQ7HCJKTW25 457730109 150.00000000 NS USD 27400.50000000 1.870307695222 Long EC CORP US N 1 N N N Schrodinger Inc/United States N/A 80810D103 342.00000000 NS USD 9032.22000000 0.616522712028 Long EC CORP US N 1 N N N Veracyte Inc 529900ESWZRHXOW27Z37 92337F107 306.00000000 NS USD 6089.40000000 0.415651235535 Long EC CORP US N 1 N N N Accolade Inc 549300PHKG8J7A22NF08 00437E102 358.00000000 NS USD 2649.20000000 0.180829515745 Long EC CORP US N 1 N N N Clover Health Investments Corp 5493000HLYOYQU6LK133 18914F103 2010.00000000 NS USD 4301.40000000 0.293605646620 Long EC CORP US N 1 N N N Butterfly Network Inc N/A 124155102 718.00000000 NS USD 2204.26000000 0.150458730325 Long EC CORP US N 1 N N N Pulmonx Corp 549300WZMFR0ZK7RJY40 745848101 186.00000000 NS USD 2737.92000000 0.186885379642 Long EC CORP US N 1 N N N QuidelOrtho Corp 549300YU8CMO9HF53113 219798105 158.00000000 NS USD 15354.44000000 1.048065812223 Long EC CORP US N 1 N N N Guardant Health Inc 254900M8C3E5VC8BR186 40131M109 566.00000000 NS USD 22832.44000000 1.558500327830 Long EC CORP US N 1 N N N CareDx Inc 549300NQOFKL9NON0U06 14167L103 270.00000000 NS USD 5799.60000000 0.395870020956 Long EC CORP US N 1 N N N QIAGEN NV 54930036WK3GMCN17Z57 000000000 1436.00000000 NS USD 67779.20000000 4.626483434099 Long EC CORP NL N 1 N N N NeoGenomics Inc N/A 64049M209 626.00000000 NS USD 5101.90000000 0.348246303179 Long EC CORP US N 1 N N N IQVIA Holdings Inc 549300W3R20NM4KQPH86 46266C105 724.00000000 NS USD 157100.76000000 10.72340870981 Long EC CORP US N 1 N N N Olink Holding AB 8945004Z7ZHV3LML4J27 680710100 742.00000000 NS USD 11278.40000000 0.769842824393 Long EC CORP SE N 1 N N N Meridian Bioscience Inc 549300ELSRZEFFFRX195 589584101 230.00000000 NS USD 6996.60000000 0.477575037696 Long EC CORP US N 1 N N N SomaLogic Inc 549300D3W3Q8CN30YO25 83444K105 882.00000000 NS USD 3986.64000000 0.272120708384 Long EC CORP US N 1 N N N Teladoc Health Inc 549300I2PVFBC9MFAC61 87918A105 840.00000000 NS USD 27896.40000000 1.904156916443 Long EC CORP US N 1 N N N Illumina Inc SQ95QG8SR5Q56LSNF682 452327109 510.00000000 NS USD 94023.60000000 6.417877871299 Long EC CORP US N 1 N N N Establishment Labs Holdings In 549300BCBQ714JNJ7V58 000000000 132.00000000 NS USD 7178.16000000 0.489967989107 Long EC CORP CR N 1 N N N Invitae Corp 549300MYI59DZW1WIX92 46185L103 1168.00000000 NS USD 2849.92000000 0.194530293489 Long EC CORP US N 1 N N N Align Technology Inc 549300N5YSE0U3LCP840 016255101 326.00000000 NS USD 77154.42000000 5.266418694784 Long EC CORP US N 1 N N N Alphatec Holdings Inc 549300EZE8CQ8K65FS24 02081G201 498.00000000 NS USD 3256.92000000 0.222311364344 Long EC CORP US N 1 N N N Pacific Biosciences of Califor 529900F1BWRE1M0KZN89 69404D108 994.00000000 NS USD 4393.48000000 0.299890857933 Long EC CORP US N 1 N N N Hologic Inc 549300DYP6F5ZJL0LB74 436440101 1172.00000000 NS USD 81219.60000000 5.543900399004 Long EC CORP US N 1 N N N Definitive Healthcare Corp N/A 24477E103 164.00000000 NS USD 3760.52000000 0.256686173392 Long EC CORP US N 1 N N N Outset Medical Inc N/A 690145107 236.00000000 NS USD 3506.96000000 0.239378634508 Long EC CORP US N 1 N N N ResMed Inc 529900T3QE5253CCXF22 761152107 338.00000000 NS USD 70854.94000000 4.836427785133 Long EC CORP US N 1 N N N Tandem Diabetes Care Inc 549300JEPFOD0K4D3I05 875372203 294.00000000 NS USD 17401.86000000 1.187818932836 Long EC CORP US N 1 N N N Intuitive Surgical Inc 54930052SRG011710797 46120E602 574.00000000 NS USD 115207.54000000 7.863854623444 Long EC CORP US N 1 N N N Natera Inc N/A 632307104 596.00000000 NS USD 21122.24000000 1.441765223712 Long EC CORP US N 1 N N N NanoString Technologies Inc 549300G4CK0Y3WRDMY89 63009R109 222.00000000 NS USD 2819.40000000 0.192447054466 Long EC CORP US N 1 N N N Masimo Corp 549300Q4A8JK0PIYCU29 574795100 290.00000000 NS USD 37894.30000000 2.586595167791 Long EC CORP US N 1 N N N 10X Genomics Inc 5493003Z6741WNLG7H43 88025U109 442.00000000 NS USD 20000.50000000 1.365197316045 Long EC CORP US N 1 N N N 1Life Healthcare Inc N/A 68269G107 1018.00000000 NS USD 7981.12000000 0.544776560737 Long EC CORP US N 1 N N N Dexcom Inc 549300YSK3QDSFR5EU59 252131107 1608.00000000 NS USD 119844.24000000 8.180347230894 Long EC CORP US N 1 N N N Veeva Systems Inc 549300YZEXPDB92M2F02 922475108 364.00000000 NS USD 72086.56000000 4.920495899350 Long EC CORP US N 1 N N N Hims & Hers Health Inc 549300ZQ4ZUYSAAX6P59 433000106 724.00000000 NS USD 3279.72000000 0.223867650377 Long EC CORP US N 1 N N N GoodRx Holdings Inc N/A 38246G108 538.00000000 NS USD 3184.96000000 0.217399507197 Long EC CORP US N 1 N N N Fulgent Genetics Inc 549300CL6P01M68QJ404 359664109 118.00000000 NS USD 6434.54000000 0.439209856652 Long EC CORP US N 1 N N N LifeStance Health Group Inc N/A 53228F101 584.00000000 NS USD 3247.04000000 0.221636973730 Long EC CORP US N 1 N N N Adaptive Biotechnologies Corp 549300ZTF7OT1FW66Q96 00650F109 812.00000000 NS USD 6569.08000000 0.448393309411 Long EC CORP US N 1 N N N Health Catalyst Inc 549300223PL6GWKVJG92 42225T107 248.00000000 NS USD 3593.52000000 0.245287060781 Long EC CORP US N 1 N N N Insulet Corp 549300TZTYD2PYN92D43 45784P101 280.00000000 NS USD 61023.20000000 4.165331309542 Long EC CORP US N 1 N N N Myriad Genetics Inc 52990044IHUOUMETT163 62855J104 424.00000000 NS USD 7704.08000000 0.525866320271 Long EC CORP US N 1 N N N Castle Biosciences Inc N/A 14843C105 136.00000000 NS USD 2985.20000000 0.203764257286 Long EC CORP US N 1 N N N Exact Sciences Corp 549300VM3X1FYD4N9Z14 30063P105 890.00000000 NS USD 35057.10000000 2.392933118088 Long EC CORP US N 1 N N N MSILF Treasury Portfolio 549300D1XR6GP7EZ0T47 61747C582 2991.62000000 NS USD 2991.62000000 0.204202474669 Long STIV RF US N 1 N N N ABIOMED Inc 5493001EZN4ZTB4Z5887 003654100 244.00000000 NS USD 60392.44000000 4.122276792952 Long EC CORP US N 1 N N N Privia Health Group Inc N/A 74276R102 324.00000000 NS USD 9434.88000000 0.644007542472 Long EC CORP US N 1 N N N Cytek Biosciences Inc 549300K2J28BOC6FBO89 23285D109 486.00000000 NS USD 5214.78000000 0.355951284206 Long EC CORP US N 1 N N N American Well Corp N/A 03044L105 1352.00000000 NS USD 5840.64000000 0.398671335816 Long EC CORP US N 1 N N N Doximity Inc N/A 26622P107 530.00000000 NS USD 18454.60000000 1.259677027508 Long EC CORP US N 1 N N N Quanterix Corp N/A 74766Q101 182.00000000 NS USD 2946.58000000 0.201128127172 Long EC CORP US N 1 N N N Burning Rock Biotech Ltd N/A 12233L107 544.00000000 NS USD 1583.04000000 0.108055396574 Long EC CORP CN N 1 N N N Twist Bioscience Corp 549300T23BL59LCOH584 90184D100 264.00000000 NS USD 9229.44000000 0.629984586215 Long EC CORP US N 1 N N N iRhythm Technologies Inc 549300FJI72RJGDQS384 450056106 150.00000000 NS USD 16204.50000000 1.106089343159 Long EC CORP US N 1 N N N 2022-08-22 First Trust Exchange-Traded Fund II Donald P. Swade Donald P. Swade Treasurer, Chief Financial Officer and Chief Accounting Officer XXXX