NPORT-P false 0001364608 XXXXXXXX S000075528 C000234707 First Trust Exchange-Traded Fund II 811-21944 0001364608 549300HY3NFBU00W8S30 120 East Liberty Drive Suite 400 Wheaton 60187 630-765-8000 First Trust Nasdaq Lux Digital Health Solutions ETF S000075528 549300D67CSMMN7O4494 2026-09-30 2026-03-31 N 2436884.17 1403.95 2435480.22 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 N Tempus AI Inc. 2549009LA0KWRAGQBX50 88023B103 1799.00000000 NS USD 81350.78000000 3.340235709243 Long EC CORP US N 1 N N N QIAGEN NV 54930036WK3GMCN17Z57 000000000 2163.00000000 NS USD 86606.52000000 3.556034628768 Long EC CORP NL N 1 N N N Twist Bioscience Corporation 549300T23BL59LCOH584 90184D100 569.00000000 NS USD 27038.88000000 1.110207333155 Long EC CORP US N 1 N N N ResMed Inc. 529900T3QE5253CCXF22 761152107 841.00000000 NS USD 188787.68000000 7.751558745979 Long EC CORP US N 1 N N N Alphatec Holdings Inc. 549300EZE8CQ8K65FS24 02081G201 2351.00000000 NS USD 25578.88000000 1.050260223423 Long EC CORP US N 1 N N N Doximity Inc N/A 26622P107 1935.00000000 NS USD 45085.50000000 1.851195490308 Long EC CORP US N 1 N N N Morgan Stanley Institutional Liquidity Funds 5493000A332Y142SOW84 61747C582 4131.94000000 NS USD 4131.94000000 0.169656068896 Long STIV RF US N 1 N N N NATERA INC 529900CQ3OZ0A0VYVU59 632307104 518.00000000 NS USD 103594.82000000 4.253568522104 Long EC CORP US N 1 N N N Guardant Health Inc 254900M8C3E5VC8BR186 40131M109 1147.00000000 NS USD 105948.39000000 4.350205315976 Long EC CORP US N 1 N N N Veracyte Inc 529900ESWZRHXOW27Z37 92337F107 865.00000000 NS USD 27861.65000000 1.143989993070 Long EC CORP US N 1 N N N QuidelOrtho Corp 549300YU8CMO9HF53113 219798105 620.00000000 NS USD 10186.60000000 0.418258375344 Long EC CORP US N 1 N N N Adaptive Biotechnologies Corp 549300ZTF7OT1FW66Q96 00650F109 2336.00000000 NS USD 32423.68000000 1.331305412942 Long EC CORP US N 1 N N N 10X Genomics Inc 5493003Z6741WNLG7H43 88025U109 1323.00000000 NS USD 28087.29000000 1.153254695700 Long EC CORP US N 1 N N N IRHYTHM HOLDINGS INC N/A 450056106 444.00000000 NS USD 52400.88000000 2.151562536607 Long EC CORP US N 1 N N N HINGE HEALTH INC N/A 433313103 498.00000000 NS USD 19202.88000000 0.788463804481 Long EC CORP US N 1 N N N Caris Life Sciences Inc. 549300LX5LO78M5VPY43 142152107 1766.00000000 NS USD 31576.08000000 1.296503241566 Long EC CORP US N 1 N N N IQVIA Holdings Inc. 549300W3R20NM4KQPH86 46266C105 1205.00000000 NS USD 205500.70000000 8.437789734954 Long EC CORP US N 1 N N N HEARTFLOW INC N/A 42238D107 1235.00000000 NS USD 30047.55000000 1.233742313045 Long EC CORP US N 1 N N N PRIVIA HEALTH GROUP INC N/A 74276R102 1501.00000000 NS USD 30875.57000000 1.267740536197 Long EC CORP US N 1 N N N ESTABLISHMENT LABS HOLDINGS INC 549300BCBQ714JNJ7V58 000000000 473.00000000 NS USD 26856.94000000 1.102736937851 Long EC CORP VG N 1 N N N TransMedics Group Inc. 549300060GVOSMWARH50 89377M109 380.00000000 NS USD 37775.80000000 1.551061662902 Long EC CORP US N 1 N N N DexCom Inc 549300YSK3QDSFR5EU59 252131107 2934.00000000 NS USD 184255.20000000 7.565456639183 Long EC CORP US N 1 N N N Globus Med Inc 5299003M2P4CIK0RF205 379577208 1128.00000000 NS USD 97188.48000000 3.990526352950 Long EC CORP US N 1 N N N Tandem Diabetes Care Inc 549300JEPFOD0K4D3I05 875372203 915.00000000 NS USD 17540.55000000 0.720209092890 Long EC CORP US N 1 N N N Veeva Systems Inc 549300YZEXPDB92M2F02 922475108 1183.00000000 NS USD 207805.78000000 8.532435545709 Long EC CORP US N 1 N N N Align Technology Inc. 549300N5YSE0U3LCP840 016255101 567.00000000 NS USD 97200.81000000 3.991032618610 Long EC CORP US N 1 N N N Neogenomics Inc 549300KN62PPGHBVXB46 64049M209 1761.00000000 NS USD 13066.62000000 0.536511029434 Long EC CORP US N 1 N N N Hims & Hers Health Inc 254900V041EIVTSB6D58 433000106 2626.00000000 NS USD 54515.76000000 2.238398799231 Long EC CORP US N 1 N N N Illumina Inc SQ95QG8SR5Q56LSNF682 452327109 801.00000000 NS USD 98731.26000000 4.053872381685 Long EC CORP US N 1 N N N Schrodinger Inc. 984500044BAE4791E559 80810D103 773.00000000 NS USD 8781.28000000 0.360556408049 Long EC CORP US N 1 N N N LifeStance Health Group Inc N/A 53228F101 2783.00000000 NS USD 17727.71000000 0.727893819642 Long EC CORP US N 1 N N N Progyny Inc N/A 74340E103 863.00000000 NS USD 14653.74000000 0.601677643680 Long EC CORP US N 1 N N N Insulet Corporation 549300TZTYD2PYN92D43 45784P101 437.00000000 NS USD 91700.08000000 3.765174491952 Long EC CORP US N 1 N N N Inspire Medical Systems Inc 549300XQQCQ7HCJKTW25 457730109 403.00000000 NS USD 20786.74000000 0.853496564221 Long EC CORP US N 1 N N N Teladoc Health Inc 549300I2PVFBC9MFAC61 87918A105 2580.00000000 NS USD 14061.00000000 0.577339938322 Long EC CORP US N 1 N N N Intuitive Surgical Inc. 54930052SRG011710797 46120E602 428.00000000 NS USD 197303.72000000 8.101224488696 Long EC CORP US N 1 N N N Waystar Holding Corp 529900QJLKXDYU36MH89 946784105 1506.00000000 NS USD 36309.66000000 1.490862446831 Long EC CORP US N 1 N N N PROCEPT BIOROBOTICS CORP N/A 74276L105 705.00000000 NS USD 17632.05000000 0.723966052165 Long EC CORP US N 1 N N N Oscar Health Inc 254900AE8KDLFDOPKZ19 687793109 4071.00000000 NS USD 46694.37000000 1.917255152250 Long EC CORP US N 1 N N N 2026-05-21 First Trust Exchange-Traded Fund II Derek Maltbie Derek Maltbie Treasurer, Chief Financial Officer and Chief Accounting Officer