X0306 4 2016-09-30 0 0001365216 Sucampo Pharmaceuticals, Inc. SCMP 0001363683 Greenleaf Peter 805 KING FARM BLVD, SUITE 550 ROCKVILLE MD 20850 0 1 0 0 Chief Executive Officer Common Stock, Class A (ESPP) 2016-09-30 5 A 0 E 640 9.38 A 2513 D The reporting person is voluntarily reporting the acquisition of common stock pursuant to the issuer's Employee Stock Purchase Plan (ESPP) for the period July 1, 2016 through September 30, 2016. This transaction is exempt under Rule 16(b)-3(c). In accordance with the ESPP, these shares were purchased at 85% of the July 1, 2016 closing price of the issuer's common stock. /s/ Peter Greenleaf 2016-10-21