X0306 4 2016-03-02 0 0001365216 Sucampo Pharmaceuticals, Inc. SCMP 0001363683 Greenleaf Peter 805 KING FARM BLVD, SUITE 550 ROCKVILLE MD 20850 0 1 0 0 Chief Executive Officer Common Stock, Class A (ESPP) 2015-12-31 5 A 0 E 476 14.70 A 476 D Employee Stock Option (right to buy) 13.80 2016-03-02 4 A 0 420000 0 A 2026-03-02 Class A Common Stock 420000 1630000 D The reporting person is voluntarily reporting the acquisition of common stock pursuant to the issuer's Employee Stock Purchase Plan (ESPP) for the period October 1, 2015 through December 31, 2015. This transaction is exempt under Rule 16(b)-3(c). In accordance with the ESPP, these shares were purchased at 85% of the closing price of the issuer's common stock on December 31, 2015. The option vests in 4 equal annual installments beginning on March 2, 2017. /s/ Peter Greenleaf 2016-03-04