X0306 4 2016-06-29 0 0001527599 Mirna Therapeutics, Inc. MIRN 0001363683 Greenleaf Peter C/O MIRNA THERAPEUTICS, INC. 3711 SOUTH MOPAC EXPRESSWAY, STE 100 AUSTIN TX 78746 1 0 0 0 Stock Option (Right to Buy) 4.74 2016-06-29 4 A 0 10000 0.00 A 2026-06-29 Common Stock 10000 10000 D The option vests and become exercisable in full on the earlier of (A) June 29, 2017 or (B) immediately prior to the next annual meeting of the Issuer's stockholders, subject to the Reporting Person continuing to provide services to the Issuer through such vesting date. /s/ Jon Irvin, Attorney-in-Fact for Peter Greenleaf 2016-09-06