144 0001363364 XXXXXXXX LIVE 0001603454 Celcuity Inc. 001-38207 2800 Campus Drive Suite 140 Minneapolis MN 55441 763-392-0123 Baker Brothers Life Sciences, L.P. Former Affiliate Common Stock Goldman Sachs & Co. LLC

200 West Street New York NY 10282

2838632 290959780.00 48766288 07/14/2026 NASDAQ Common Stock 05/16/2025 Purchases of shares of common stock in the open market See Remark 2 Purchases from counterparties in open market transactions N 2838632 05/19/2025 Cash Y (1) Baker Brothers Life Sciences, L.P. is affiliated with 667, L.P. Baker Bros. Advisors LP is the investment adviser to 667, L.P. and Baker Brothers Life Sciences, L.P. 667, L.P. is filing separately for the sale of 261,368 shares of common stock ("Common Stock") of Celcuity Inc. (the "Issuer"), which along with the reported sales in this form by Baker Brothers Life Sciences, L.P. totals 3,100,000 shares of Common Stock. (2) Shares of common stock to be sold were purchased between 5/16/2025 and 12/13/2024 in various open market transactions. 07/14/2026 By: BAKER BROS. ADVISORS LP, mgmt company and IA to Baker Brothers Life Sciences, L.P., /s/ Scott L. Lessing, President