<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: Baker Brothers Life Sciences LP -->
          <cik>0001363364</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001359931</issuerCik>
      <issuerName>Protara Therapeutics, Inc.</issuerName>
      <secFileNumber>001-36694</secFileNumber>
      <issuerAddress>
        <com:street1>345 Park Avenue South</com:street1>
        <com:street2>Third Floor</com:street2>
        <com:city>New York</com:city>
        <com:stateOrCountry>NY</com:stateOrCountry>
        <com:zipCode>10010</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>646-844-0337</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Baker Brothers Life Sciences, L.P.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Former Affiliate</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Jefferies LLC</name>
        <address>
          <com:street1>520 Madison Avenue</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10022</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>300176</noOfUnitsSold>
      <aggregateMarketValue>1605942.00</aggregateMarketValue>
      <noOfUnitsOutstanding>55060500</noOfUnitsOutstanding>
      <approxSaleDate>04/23/2026</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <acquiredDate>09/22/2020</acquiredDate>
      <natureOfAcquisitionTransaction>See Remark 2</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Underwriter</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>300176</amountOfSecuritiesAcquired>
      <paymentDate>09/24/2020</paymentDate>
      <natureOfPayment>See Remark 2</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Baker Brothers Life Sciences, L.P.</name>
        <address>
          <com:street1>860 Washington Street, 3rd Floor</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10014</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <saleDate>02/24/2026</saleDate>
      <amountOfSecuritiesSold>322039</amountOfSecuritiesSold>
      <grossProceeds>1944922.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Baker Brothers Life Sciences, L.P.</name>
        <address>
          <com:street1>860 Washington Street, 3rd Floor</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10014</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <saleDate>02/25/2026</saleDate>
      <amountOfSecuritiesSold>947479</amountOfSecuritiesSold>
      <grossProceeds>5501316.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Baker Brothers Life Sciences, L.P.</name>
        <address>
          <com:street1>860 Washington Street, 3rd Floor</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10014</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <saleDate>03/04/2026</saleDate>
      <amountOfSecuritiesSold>424125</amountOfSecuritiesSold>
      <grossProceeds>2654641.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Baker Brothers Life Sciences, L.P.</name>
        <address>
          <com:street1>860 Washington Street, 3rd Floor</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10014</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <saleDate>03/06/2026</saleDate>
      <amountOfSecuritiesSold>461723</amountOfSecuritiesSold>
      <grossProceeds>2701080.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <remarks>(1) Baker Brothers Life Sciences, L.P. is affiliated with 667, L.P. Baker Bros. Advisors LP is the investment adviser to 667, L.P. and Baker Brothers Life Sciences, L.P. 667, L.P. is filing separately for the sale of 24,802 shares of common stock ("Common Stock") of Protara Therapeutics, Inc. (the "Issuer"), which along with the reported sales in this form by Baker Brothers Life Sciences, L.P. totals 324,978 shares of Common Stock. (2) Common Stock converted from Series 1 Preferred.</remarks>
    <noticeSignature>
      <noticeDate>04/23/2026</noticeDate>
      <signature>By: BAKER BROS. ADVISORS LP, mgmt company and IA to Baker Brothers Life Sciences, L.P., /s/ Scott L. Lessing, President</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
