144 0001363364 XXXXXXXX LIVE 0001359931 Protara Therapeutics, Inc. 001-36694 345 Park Avenue South Third Floor New York NY 10010 646-844-0337 Baker Brothers Life Sciences, L.P. Former Affiliate Common Stock Canaccord Genuity LLC

99 High Street, Suite 1200 Boston MA 02110

322039 1944922.00 53587260 02/24/2026 NASDAQ Common Stock 12/08/2025 See Remark 2 Underwriter N 322039 12/08/2025 Cash Y (1) Baker Brothers Life Sciences, L.P. is affiliated with 667, L.P. Baker Bros. Advisors LP is the investment adviser to 667, L.P. and Baker Brothers Life Sciences, L.P. 667, L.P. is filing separately for the sale of 26,755 shares of common stock ("Common Stock") of Protara Therapeutics, Inc. (the "Issuer"), which along with the reported sales in this form by Baker Brothers Life Sciences, L.P. totals 348,794 shares of Common Stock. (2) Common Stock acquired in underwritten public offering. 02/24/2026 By: BAKER BROS. ADVISORS LP, mgmt company and IA to Baker Brothers Life Sciences, L.P., /s/ Scott L. Lessing, President