X0306 4 2018-03-12 0 0001362959 Rosetta Genomics Ltd. ROSG 0001535610 SABBY MANAGEMENT, LLC 10 MOUNTAINVIEW ROAD SUITE 205 UPPER SADDLE RIVER NJ 07458 0 0 1 0 0001561018 Sabby Healthcare Master Fund, Ltd. C/O SABBY MANAGEMENT, LLC 10 MOUNTAINVIEW ROAD, SUITE 205 UPPER SADDLE RIVER NJ 07458 0 0 1 0 ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 20373 0.4199 A 595094 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 454 0.401 A 595548 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 2604 0.4199 A 598152 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 11521 0.41 A 609673 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 21800 0.4117 A 631473 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 24600 0.4185 A 656073 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 24162 0.4186 A 680235 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 10605 0.4189 A 690840 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 12390 0.4101 A 703230 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-12 4 P 0 10000 0.42 A 713230 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-13 4 P 0 30990 0.4203 A 744220 I See Footnotes ADR Shares (each one equal to 2 ordinary shares) 2018-03-13 4 P 0 6329 0.42 A 750549 I See Footnotes This Form 4 is being filed by Sabby Healthcare Master Fund, Ltd. ("SHMF"), Sabby Volatility Warrant Master Fund, Ltd. ("SVWMF"), Sabby Management, LLC ("Advisor") and Hal Mintz. Advisor is the investment manager of SHMF and SVWMF. Mr. Mintz is the manager of Advisor. The amounts reported herein reflect the entire amount of Issuer's ADR shares held by SHMF and SVWMF as of each transaction date. Each of Advisor and Mr. Mintz disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934 ("Section 16"), beneficial ownership of such securities, except to the extent of its/his pecuniary interest therein, and this report shall not be deemed as admission that either Advisor or Mr. Mintz is the beneficial owner of such securities for purposes of Section 16 or otherwise. /s/ Robert Grundstein, COO and General Counsel of Sabby Management, LLC 2018-03-14