CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
Revenue			$ 0
Expenses:
General and administrative	$ 1,471,191	$ 2,523,104	6,825,473	$ 8,542,635
Research and development	(38,256)	6,096,424	4,761,844	20,252,415
Impairment charge	5,169,000		5,169,000
Restructuring charges	1,458,065		3,499,960
Change in fair value of contingent consideration	1,164,000	1,123,000	3,326,000	3,252,000
Total expenses	9,224,000	9,742,528	23,582,277	32,047,050
Loss from operations	(9,224,000)	(9,742,528)	(23,582,277)	(32,047,050)
Change in fair value of derivative liabilities	23,481	431,358	96,642	2,073,581
Debt exchange expense				(818,541)
Loss on sale of equipment			(153,572)
Interest and other income	7,926	21,614	31,071	82,754
Interest expense	(1,758,926)	(1,606,402)	(5,155,254)	(4,742,731)
Loss before income tax benefit	(10,951,519)	(10,895,958)	(28,763,390)	(35,451,987)
Income tax benefit	2,317,000		2,317,000
Net loss	$ (8,634,519)	$ (10,895,958)	$ (26,446,390)	$ (35,451,987)
Per share information:
Net loss per common share: Basic (in dollars per share)	$ (0.35)	$ (0.46)	$ (1.07)	$ (1.52)
Net loss per common share: Diluted (in dollars per share)	$ (0.35)	$ (0.46)	$ (1.07)	$ (1.52)
Weighted average shares outstanding: Basic (in shares)	24,769,083	23,830,978	24,769,083	23,329,464
Weighted average shares outstanding: Diluted (in shares)	24,769,083	23,864,931	24,769,083	23,369,342
Net loss	$ (8,634,519)	$ (10,895,958)	$ (26,446,390)	$ (35,451,987)
Foreign currency gains (losses)	(20,216)	(13,300)	(15,623)	19,482
Unrealized gains (losses) on available-for-sale securities		3,796	971	9,645
Comprehensive loss	$ (8,654,735)	$ (10,905,462)	$ (26,461,042)	$ (35,422,860)