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Fair Value Measurements (Level 3) (Details) - USD ($)
3 Months Ended 9 Months Ended
Nov. 02, 2016
Sep. 30, 2016
Sep. 30, 2016
Sep. 30, 2015
Changes in the fair value of Level 3 liabilities        
Balance at the beginning of the period     $ 21,199,877 $ 34,147,713
Change in Fair Value     3,229,358 1,178,419
Balance at the end of the period   $ 24,429,235 24,429,235 35,160,175
Impairment charge   5,169,000 5,169,000  
Interest make-whole derivative        
Changes in the fair value of Level 3 liabilities        
Balance at the beginning of the period     55,000 2,400,000
Conversions       (165,957)
Change in Fair Value     (33,000) (1,889,043)
Balance at the end of the period   22,000 22,000 345,000
Shape contingent consideration        
Changes in the fair value of Level 3 liabilities        
Balance at the beginning of the period     21,080,000 31,491,686
Change in Fair Value     3,326,000 3,252,000
Balance at the end of the period   24,406,000 24,406,000 34,743,686
Common stock warrant liability        
Changes in the fair value of Level 3 liabilities        
Balance at the beginning of the period     64,877 256,027
Change in Fair Value     (63,642) (184,538)
Balance at the end of the period   1,235 1,235 $ 71,489
Shape Pharmaceuticals        
Changes in the fair value of Level 3 liabilities        
Fair value of assets   12,000,000 $ 12,000,000  
Impairment charge   $ 5,200,000    
Medivir        
Changes in the fair value of Level 3 liabilities        
Consideration for sale $ 12,000,000