CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
Revenue			$ 0
Expenses:
General and administrative	$ 2,382,147	$ 2,883,682	5,354,282	$ 6,019,531
Research and development	1,498,561	7,709,798	4,800,100	14,155,991
Restructuring charges	28,871		2,041,895
Change in fair value of contingent consideration	1,108,000	1,081,000	2,162,000	2,129,000
Total expenses	5,017,579	11,674,480	14,358,277	22,304,522
Loss from operations	(5,017,579)	(11,674,480)	(14,358,277)	(22,304,522)
Change in fair value of derivative liabilities	(19,791)	1,352,557	73,161	1,642,223
Debt exchange expense				(818,541)
Loss on sale of equipment			(153,572)
Interest and other income	8,476	21,946	23,145	61,140
Interest expense	(1,717,707)	(1,573,070)	(3,396,328)	(3,136,329)
Net loss	$ (6,746,601)	$ (11,873,047)	$ (17,811,871)	$ (24,556,029)
Per share information:
Net loss per common share: Basic (in dollars per share)	$ (0.27)	$ (0.51)	$ (0.72)	$ (1.06)
Net loss per common share: Diluted (in dollars per share)	$ (0.27)	$ (0.51)	$ (0.72)	$ (1.07)
Weighted average shares outstanding: Basic (in shares)	24,769,083	23,332,096	24,769,083	23,074,550
Weighted average shares outstanding: Diluted (in shares)	24,769,083	23,370,335	24,769,083	23,116,253
Net loss	$ (6,746,601)	$ (11,873,047)	$ (17,811,871)	$ (24,556,029)
Foreign currency gains (losses)	(6,690)	11,266	4,593	32,782
Unrealized gains (losses) on available-for-sale securities		(3,430)	971	5,849
Comprehensive loss	$ (6,753,291)	$ (11,865,211)	$ (17,806,307)	$ (24,517,398)