CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
Revenue	$ 0
Expenses:
General and administrative	11,098,577	$ 10,926,777
Research and development	27,401,669	20,286,826
Impairment of goodwill	16,902,466
Change in fair value of contingent consideration	(10,411,686)	2,572,000
Total expenses	44,991,026	33,785,603
Loss from operations	(44,991,026)	(33,785,603)
Change in fair value of derivative liabilities	2,370,193	1,073,198
Debt exchange expense	(818,541)
Interest and other income	99,605	112,815
Interest expense	(6,384,285)	(3,359,389)
Net loss	$ (49,724,054)	$ (35,958,979)
Per share information:
Net loss per common share: Basic (in dollars per share)	$ (2.10)	$ (1.61)
Net loss per common share: Diluted (in dollars per share)	$ (2.10)	$ (1.63)
Weighted average shares outstanding: Basic (in shares)	23,692,327	22,290,069
Weighted average shares outstanding: Diluted (in shares)	23,730,375	22,351,689
Net loss	$ (49,724,054)	$ (35,958,979)
Foreign currency gains losses	(1,759)	(69,031)
Unrealized gains/(losses) on available-for-sale securities	7,146	(8,117)
Comprehensive loss	$ (49,718,667)	$ (36,036,127)