Consolidated Statements of Changes in Stockholders' Equity - USD ($) $ in Thousands	Total	Common stock	Additional paid-in capital	Accumulated other comprehensive income (loss)	Accumulated deficit
Balance (in shares) at Dec. 31, 2018		88,730,640
Balance at Dec. 31, 2018	$ 125,370	$ 89	$ 266,882	$ (3,633)	$ (137,968)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense	46,139		46,139
Common stock issued under employee stock plans, net (shares)		3,019,293
Common stock issued under employee stock plans, net	(2,397)	$ 3	(2,400)
Realized and unrealized gains (losses) on derivative	3,158			3,158
Unrealized gains (losses) in available for sale securities	26			26
Net loss	(78,764)				(78,764)
Balance (in shares) at Dec. 31, 2019		91,749,933
Balance at Dec. 31, 2019	93,532	$ 92	310,621	(449)	(216,732)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense	68,585		68,585
Common stock issued under employee stock plans, net (shares)		3,600,003
Common stock issued under employee stock plans, net	9,791	$ 3	9,788
Issuance of common stock from acquisitions (in shares)		106,926
Issuance of common stock from acquisitions	4,198	$ 0	4,198
Fair value of replacement equity awards attributable to pre-acquisition service	709		709
Realized and unrealized gains (losses) on derivative	9,838			9,838
Unrealized gains (losses) in available for sale securities	(18)			(18)
Purchase of capped calls related to Convertible senior notes	(29,348)		(29,348)
Equity component of Convertible senior notes, net	30,794		30,794
Net loss	(94,010)				(94,010)
Balance (in shares) at Dec. 31, 2020		95,456,862
Balance at Dec. 31, 2020	94,071	$ 95	395,347	9,371	(310,742)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of Common stock in connection with follow-on offering, net of issuance costs of $17,466 (in shares)		7,961,538
Issuance of Common stock in connection with follow-on offering, net of issuance costs of $17,466	500,034	$ 8	500,026
Stock-based compensation expense	109,779		109,779
Common stock issued under employee stock plans, net (shares)		4,090,696
Common stock issued under employee stock plans, net	12,858	$ 5	12,853
Realized and unrealized gains (losses) on derivative	(3,285)			(3,285)
Unrealized gains (losses) in available for sale securities	(3)			(3)
Net loss	(116,861)				(116,861)
Balance (in shares) at Dec. 31, 2021		107,509,096
Balance at Dec. 31, 2021	$ 596,593	$ 108	$ 1,018,005	$ 6,083	$ (427,603)