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Income Taxes (Details Textual) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Tax Credit Carryforward [Line Items]      
Valuation allowance, deferred tax asset, increase (decrease), amount $ 14,943 $ 22,818  
Unrecognized tax benefits 4,690 $ 3,201 $ 1,954
Unrecognized tax benefits that would impact effective tax rate 4,407    
Unrecognized tax benefits, income tax penalties and interest expense 538    
Domestic Tax Authority      
Tax Credit Carryforward [Line Items]      
Operating loss carryforwards 207,768    
Operating loss carryforwards, subject to expiration 22,907    
State and Local Jurisdiction      
Tax Credit Carryforward [Line Items]      
Operating loss carryforwards 146,121    
Operating loss carryforwards, subject to expiration 129,143    
Foreign Tax Authority      
Tax Credit Carryforward [Line Items]      
Operating loss carryforwards 1,321    
Deferred income tax asset $ 1,131    
Israel Tax Authority | Foreign Tax Authority | VSL | Minimum      
Tax Credit Carryforward [Line Items]      
Tax rate for amount of dividends distributed, other than complete liquidation 10.00%    
Israel Tax Authority | Foreign Tax Authority | VSL | Maximum      
Tax Credit Carryforward [Line Items]      
Tax rate for amount of dividends distributed, other than complete liquidation 25.00%    
Research Tax Credit Carryforward | Domestic Tax Authority      
Tax Credit Carryforward [Line Items]      
Tax credit carryforward, amount $ 1,412    
Retention | Domestic Tax Authority      
Tax Credit Carryforward [Line Items]      
Tax credit carryforward, amount 24    
Foreign Tax Credit | Domestic Tax Authority      
Tax Credit Carryforward [Line Items]      
Tax credit carryforward, amount 190    
Ireland Employment | Domestic Tax Authority      
Tax Credit Carryforward [Line Items]      
Tax credit carryforward, amount $ 16