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Stockholders' Equity - Outstanding Options Granted to Consultants for Sales and Pre-marketing Services (Details)
9 Months Ended
Sep. 30, 2018
$ / shares
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 0
Options exercisable at the end of the year (in shares) 722,216
Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 24,718
Options exercisable at the end of the year (in shares) 23,101
February 2013 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 1,500
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 12.47
Options exercisable at the end of the year (in shares) 1,500
Exercisable through February 2023
August 2013 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 4,000
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 21.14
Options exercisable at the end of the year (in shares) 4,000
Exercisable through August 2023
March 2014 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 5,550
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 39.86
Options exercisable at the end of the year (in shares) 5,550
Exercisable through March 2024
May 2014 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 3,700
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 22.01
Options exercisable at the end of the year (in shares) 3,700
Exercisable through May 2024
November 2014 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 6,693
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 21.66
Options exercisable at the end of the year (in shares) 6,296
Exercisable through November 2024
May 2015 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 1,137
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 19.51
Options exercisable at the end of the year (in shares) 805
Exercisable through May 2025
February 2016 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 2,138
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 16.87
Options exercisable at the end of the year (in shares) 1,250
Exercisable through February 2026