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Stockholders' Equity - Outstanding Options Granted to Consultants for Sales and Pre-marketing Services (Details)
6 Months Ended
Jun. 30, 2018
$ / shares
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 0
Options exercisable at the end of the year (in shares) 765,242
Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 28,136
Options exercisable at the end of the year (in shares) 25,632
February 2013 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 1,500
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 12.47
Options exercisable at the end of the year (in shares) 1,500
Exercisable through February 2023
August 2013 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 4,188
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 21.14
Options exercisable at the end of the year (in shares) 4,188
Exercisable through August 2023
March 2014 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 7,300
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 39.86
Options exercisable at the end of the year (in shares) 7,300
Exercisable through March 2024
May 2014 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 5,000
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 22.01
Options exercisable at the end of the year (in shares) 5,000
Exercisable through May 2024
November 2014 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 6,768
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 21.66
Options exercisable at the end of the year (in shares) 5,765
Exercisable through November 2024
May 2015 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 1,200
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 19.51
Options exercisable at the end of the year (in shares) 742
Exercisable through May 2025
February 2016 | Consultants  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Options for shares of common stock (in shares) 2,180
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 16.87
Options exercisable at the end of the year (in shares) 1,137
Exercisable through February 2026