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SHARE-BASED COMPENSATION PLANS - Stock Options Outstanding and Exercisable (Details) - $ / shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Option outstanding (in shares) 2,140,618    
Weighted-average remaining contractual term, option outstanding (in years) 8 years 5 months 23 days 8 years 2 months 8 days 7 years 9 months 25 days
Weighted-average exercise price, option outstanding (in dollars per share) $ 15.01    
Option exercisable (in shares) 718,123    
Weighted-average remaining contractual term, option exercisable (in years) 6 years 11 months 23 days    
Weighted-average exercise price (in dollars per share) $ 36.42    
$1.73 to $2.87      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Exercise Price - minimum (in dollars per share) 1.73    
Exercise Price - maximum (in dollars per share) $ 2.87    
Option outstanding (in shares) 215,000    
Weighted-average remaining contractual term, option outstanding (in years) 9 years 10 months 20 days    
Weighted-average exercise price, option outstanding (in dollars per share) $ 1.81    
Option exercisable (in shares) 0    
Weighted-average remaining contractual term, option exercisable (in years) 0 years    
Weighted-average exercise price (in dollars per share) $ 0    
$2.88 to $2.93      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Exercise Price - minimum (in dollars per share) 2.88    
Exercise Price - maximum (in dollars per share) $ 2.93    
Option outstanding (in shares) 665,000    
Weighted-average remaining contractual term, option outstanding (in years) 9 years 7 months 13 days    
Weighted-average exercise price, option outstanding (in dollars per share) $ 2.88    
Option exercisable (in shares) 0    
Weighted-average remaining contractual term, option exercisable (in years) 0 years    
Weighted-average exercise price (in dollars per share) $ 0    
$2.94 to $3.01      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Exercise Price - minimum (in dollars per share) 2.94    
Exercise Price - maximum (in dollars per share) $ 3.01    
Option outstanding (in shares) 506,000    
Weighted-average remaining contractual term, option outstanding (in years) 8 years 11 months 12 days    
Weighted-average exercise price, option outstanding (in dollars per share) $ 2.97    
Option exercisable (in shares) 253,000    
Weighted-average remaining contractual term, option exercisable (in years) 8 years 11 months 12 days    
Weighted-average exercise price (in dollars per share) $ 2.97    
$3.02 to $16.15      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Exercise Price - minimum (in dollars per share) 3.02    
Exercise Price - maximum (in dollars per share) $ 16.15    
Option outstanding (in shares) 475,076    
Weighted-average remaining contractual term, option outstanding (in years) 7 years 3 months 25 days    
Weighted-average exercise price, option outstanding (in dollars per share) $ 9.97    
Option exercisable (in shares) 207,374    
Weighted-average remaining contractual term, option exercisable (in years) 6 years 1 month 24 days    
Weighted-average exercise price (in dollars per share) $ 11.97    
$16.16 to $234.70      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Exercise Price - minimum (in dollars per share) 16.16    
Exercise Price - maximum (in dollars per share) $ 234.70    
Option outstanding (in shares) 279,542    
Weighted-average remaining contractual term, option outstanding (in years) 5 years 9 months 25 days    
Weighted-average exercise price, option outstanding (in dollars per share) $ 84.39    
Option exercisable (in shares) 257,749    
Weighted-average remaining contractual term, option exercisable (in years) 5 years 8 months 15 days    
Weighted-average exercise price (in dollars per share) $ 88.94