X0306 4 2018-02-05 0 0001358403 BELLICUM PHARMACEUTICALS, INC BLCM 0001730229 Grossman William C/O BELLICUM PHARMACEUTICALS, INC. 2130 W. HOLCOMBE BLVD., STE. 800 HOUSTON TX 77030 0 1 0 0 Sr. VP, Chief Medical Officer Common Stock 2018-02-05 4 A 0 30000 0.00 A 30000 D Employee Stock Option (right to buy) 5.61 2018-02-05 4 A 0 175000 0.00 A 2028-02-04 Common Stock 175000 175000 D Represents grant of restricted stock units payable solely in common stock that vest in four equal annual installments on each anniversary of February 5, 2018. 25% of the shares subject to the stock option vest and become exercisable on February 5, 2019, and the remaining shares subject to the stock option vest and become exercisable in 36 equal monthly installments thereafter. /s/ Alan Musso, Attorney-in-Fact 2018-02-07