SCHEDULE 13G/A 0001591986-24-000004 0001591986 XXXXXXXX LIVE 1 Common Stock, par value $0.000005 per share 12/31/2024 0001357874 PRECISION BIOSCIENCES INC 74019P207 302 EAST PETTIGREW STREET SUITE A-100 DURHAM NC 27701 Rule 13d-1(b) Aquilo Capital, L.P. DE 0.00 521372.00 0.00 521372.00 521372.00 6.6 PN Aquilo Capital Management, LLC CA 0.00 791862.00 0.00 791862.00 791862.00 9.9 IA HC OO Marc Schneidman X1 0.00 791862.00 0.00 791862.00 791862.00 9.9 HC IN PRECISION BIOSCIENCES INC 302 EAST PETTIGREW STREET, SUITE A-100, DURHAM, NORTH CAROLINA, 27701. This statement is filed by the entities and persons listed below, who are collectively referred to herein as "Reporting Persons", with respect to the Common Stock (as defined in Item 2(d) below) of the Company: (i) Aquilo Capital, L.P. (ii) Aquilo Capital Management, LLC (iii) Marc Schneidman (i) Aquilo Capital, L.P. One Letterman Drive, Suite D4900 Building D, The Presidio San Francisco, CA 94129 (ii) Aquilo Capital Management, LLC One Letterman Drive, Suite D4900 Building D, The Presidio San Francisco, CA 94129 (iii) Marc Schneidman c/o Aquilo Capital Management, LLC One Letterman Drive, Suite D4900 Building D, The Presidio San Francisco, CA 94129 (i) Aquilo Capital, L.P. - DE (ii) Aquilo Capital Management, LLC - CA (iii) Marc Schneidman - USA N IA HC Aquilo Capital Management, LLC is an investment adviser that is registered under the Investment Advisers Act of 1940. Aquilo Capital Management, LLC, which serves as the general partner and investment manager to investment funds, including but not limited to, Aquilo Capital, L.P., (collectively the "Funds"), may be deemed to be the beneficial owner of all shares of Common Stock held by the Funds. Mr. Schneidman, as Managing Member of Aquilo Capital Management, LLC, with the power to exercise investment and voting discretion, may be deemed to be the beneficial owner of all shares of Common Stock held by the Funds. Pursuant to Rule 13d-4 under the Securities Exchange Act of 1934, as amended, each of the Funds expressly disclaims beneficial ownership over any of the securities reported in this statement, and the filing of this statement shall not be construed as an admission that any of the Funds are the beneficial owner of any of the securities reported herein. Aquilo Capital L.P Amount beneficially owned: 521,372 Aquilo Capital Management, LLC Amount beneficially owned: 791,862 Marc Schneidman Amount beneficially owned: 791,862 This calculation for Aquilo Capital, L.P. is comprised of beneficial ownership of 521,372 shares of Common Stock which consists of (i) 312,372 shares of Common Stock and (ii) 209,000 shares issuable upon exercise of warrants held by Aquilo Capital, LP (the "Warrants"). All such shares of Common Stock in the aggregate represent beneficial ownership of approximately 6.6% of the Common Stock based on (i) 7,671,059 shares of Common Stock outstanding as of October 31, 2024 as represented in the 10Q filed by the Issuer with the Securities and Exchange Commission ("SEC") on November 4, 2024, plus (ii) 209,000 shares of Common Stock issuable upon the exercise of the Warrants. The amount for Aquilo Capital Management, LLC and Marc Schneidman is comprised of beneficial ownership of 791,862 shares of Common Stock which consists of (i) 536,376 shares of Common Stock and (ii) 255,486 shares issuable upon exercise of warrants held by Aquilo Capital Management, LLC (the "Warrants"). All such shares of Common Stock in the aggregate represent beneficial ownership of approximately 9.99% of the Common Stock based on (i) 7,671,059 shares of Common Stock outstanding as of October 31, 2024 as represented in the 10Q filed by the Issuer with the Securities and Exchange Commission ("SEC") on November 4, 2024, plus (ii) 255,486 shares of Common Stock issuable upon the exercise of the Warrants. The foregoing excludes 57,014 shares of Common Stock issuable upon exercise of the Warrants because the Warrants contain a blocker provision under which the holder does not have the right to exercise the Warrants to the extent that together with the holder's affiliates and any other person or entity acting as a group together with the holder of any or the holder's affiliates, owns more than 9.99% of the Common Stock. Aquilo Capital LP Percent of Class: 6.6% Aquilo Capital Management, LLC Percent of Class: 9.9% Marc Schneidman Percent of Class: 9.9% Aquilo Capital L.P Sole power to vote or to direct the vote: 0 Aquilo Capital Management, LLC Sole power to vote or to direct the vote: 0 Marc Schneidman Sole power to vote or to direct the vote: 0 Aquilo Capital L.P Shared power to vote or to direct the vote: 521,372 Aquilo Capital Management, LLC Shared power to vote or to direct the vote: 791,862 Marc Schneidman Shared power to vote or to direct the vote: 791,862 Aquilo Capital L.P Sole power to dispose or to direct the disposition of: 0 Aquilo Capital Management, LLC Sole power to dispose or to direct the disposition of: 0 Marc Schneidman Sole power to dispose or to direct the disposition of: 0 Aquilo Capital L.P Shared power to dispose or to direct the disposition of: 521,372 Aquilo Capital Management, LLC Shared power to dispose or to direct the disposition of: 791,862 Marc Schneidman Shared power to dispose or to direct the disposition of: 791,862 Y N The Funds have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the shares of Common Stock covered by this Statement. N See Note Above. Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Aquilo Capital, L.P. /s/ Marc Schneidman 02/14/2025 Aquilo Capital Management, LLC /s/ Marc Schneidman 02/14/2025 Marc Schneidman /s/ Marc Schneidman 02/14/2025