X0306 4 2022-03-17 0 0001357874 PRECISION BIOSCIENCES INC DTIL 0001590030 Kelly John Alexander C/O PRECISION BIOSCIENCES, INC. 302 E. PETTIGREW STREET, SUITE A-100 DURHAM NC 27701 0 1 0 0 Chief Financial Officer Common Stock 2022-03-17 4 P 0 16677 3.08 A 36189 D The price reported in Column 4 is a weighted average price. These shares were acquired in multiple transactions at prices ranging from $3.05 to $3.09. The reporting person undertakes to provide the Company, any security holder of the Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the range set forth in this footnote. /s/ John Alexander Kelly 2022-03-21