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Note 7 - Common Stock Warrants - Summary of Warrant Activity (Details) - $ / shares
9 Months Ended 12 Months Ended
Sep. 30, 2022
Dec. 31, 2021
Warrants and Rights Note Disclosure [Abstract]    
Warrants outstanding, balance (in shares) 7,181,741  
Warrants outstanding, weighted average exercise price (in dollars per share) $ 0.44 $ 5.96
Warrants outstanding, December 31, 2021 3 years 14 days 4 years 5 months 12 days
Class of warrant or right, issued during period (in shares) 119,827,491  
Granted, weighted average exercise price (in dollars per share) $ 0.28  
Granted, weighted average remaining contractual life 3 years 14 days  
Exercised (in shares) (3,994,302)  
Exercised, weighted average exercise price $ 3.88  
Exercised, weighted average remaining contractual life 4 years 1 month 9 days  
Forfeited, expired or cancelled (in shares) (90,018)  
Forfeited, expired, or cancelled, weighted average exercise price $ 81.37  
Warrants outstanding, balance (in shares) 122,924,912 7,181,741