X0306 4 2013-09-11 1 0001356857 Trius Therapeutics Inc TSRX 0001478916 Schmid John P. C/O TRIUS THERAPEUTICS, INC. 6310 NANCY RIDGE DR, # 105 SAN DIEGO CA 92121 0 1 0 0 Chief Financial Officer Common Stock 2013-09-11 4 D 0 107639 D 0 D Stock Option (right to buy) 1.29 2013-09-11 4 D 0 28720 12.21 D 2018-05-20 Common Stock 28720 0 D Stock Option (right to buy) 1.29 2013-09-11 4 D 0 8138 12.21 D 2019-01-08 Common Stock 8138 0 D Stock Option (right to buy) 3.50 2013-09-11 4 D 0 75000 10.00 D 2020-11-02 Common Stock 75000 0 D Stock Option (right to buy) 4.80 2013-09-11 4 D 0 85000 8.70 D 2022-03-07 Common Stock 85000 0 D Stock Option (right to buy) 6.13 2013-09-11 4 D 0 140000 7.37 D 2023-03-06 Common Stock 140000 0 D Pursuant the terms of that certain Agreement and Plan of Merger, dated as of July 30, 2013, by and among Trius Therapeutics, Inc., Cubist Pharmaceuticals, Inc., and BRGO Corporation (the "Merger Agreement") and the Offer (as defined in the Merger Agreement), each share of Trius common stock was validly tendered for $13.50 per share in cash plus one non-transferrable contingent value right for each share (each a "CVR"), which represents the contractual right to receive up to $2.00 per share upon the achievement of certain milestones, subject to any required withholding of taxes. Pursuant the terms of the Merger Agreement and the Offer, each stock option that was outstanding and unexercised as of the Offer Acceptance Time (as defined in the Merger Agreement), whether or not vested, was cancelled and converted into the right to receive $13.50 per share (minus the exercise price of the option) in cash plus one CVR which represents the contractual right to receive up to $2.00 per share upon the achievement of certain milestones, subject to any required withholding of taxes. /s/ Michael Morneau, Attorney-in-Fact 2013-09-12