Composition of Other Balance Sheet Items - Property and Equipment (Details) - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Property and equipment
Property and equipment, gross	$ 29,388	$ 28,935
Less accumulated depreciation and amortization	(17,843)	(15,405)
Property and equipment, net	11,545	13,530
Depreciation and amortization expense	2,400	2,500	$ 3,000
Lab equipment and furniture
Property and equipment
Property and equipment, gross	13,370	13,069
Leasehold improvements
Property and equipment
Property and equipment, gross	14,023	14,023
Software
Property and equipment
Property and equipment, gross	883	883
Computer equipment
Property and equipment
Property and equipment, gross	$ 1,112	$ 960

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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