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Composition of Other Balance Sheet Items - Property and Equipment (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Property and equipment      
Property and equipment, gross $ 28,935 $ 28,222  
Less accumulated depreciation and amortization (15,405) (13,049)  
Property and equipment, net 13,530 15,173  
Depreciation and amortization expense 2,500 3,000 $ 2,600
Lab equipment and furniture      
Property and equipment      
Property and equipment, gross 13,069 12,127  
Leasehold improvements      
Property and equipment      
Property and equipment, gross 14,023 14,023  
Software      
Property and equipment      
Property and equipment, gross 883 883  
Computer equipment      
Property and equipment      
Property and equipment, gross 960 983  
Construction-in-progress      
Property and equipment      
Property and equipment, gross $ 0 $ 206