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Composition of Other Balance Sheet Items - Property and Equipment (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2022
Property and equipment          
Property and equipment, gross $ 28,604   $ 28,604   $ 28,222
Less accumulated depreciation and amortization (14,916)   (14,916)   (13,049)
Property and equipment, net 13,688   13,688   15,173
Depreciation and amortization expense 600 $ 800 1,900 $ 2,200  
Lab equipment and furniture          
Property and equipment          
Property and equipment, gross 12,620   12,620   12,127
Leasehold improvements          
Property and equipment          
Property and equipment, gross 14,023   14,023   14,023
Software          
Property and equipment          
Property and equipment, gross 883   883   883
Computer equipment          
Property and equipment          
Property and equipment, gross 1,078   1,078   983
Construction-in-progress          
Property and equipment          
Property and equipment, gross $ 0   $ 0   $ 206