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Share-Based Payments
9 Months Ended
Sep. 30, 2022
Share-Based Payment Arrangement [Abstract]  
Share-Based Payments Share-Based Payments
Share-based compensation expense is as follows (dollars in thousands):
Three Months Ended
September 30,
Nine Months Ended
September 30,
2022202120222021
(unaudited)(unaudited)
Research and development$825 $615 $2,284 $1,909 
Selling, general and administrative4,160 3,412 11,023 11,965 
Total$4,985 $4,027 $13,307 $13,874 
Stock Option and Stock Appreciation Rights
The following table summarizes stock option and stock appreciation rights (SAR) activities:
Number of
Options & SARs
Weighted
Average
Exercise Price
(per share)
Weighted
Average
Remaining
Contractual
Term (in years)
Outstanding, December 31, 20215,774,076 $24.15 5.95
Granted 1,046,785 $31.95 
Exercised (673,120)$12.79 
Forfeited (145,473)$30.06 
Outstanding, September 30, 2022 (unaudited)6,002,268 $26.64 6.29
As of December 31, 2021:
Vested and expected to vest5,774,076 $24.15 5.95
Exercisable3,651,824 $21.29 4.53
As of September 30, 2022 (unaudited):
Vested and expected to vest6,002,268 $26.64 6.29
Exercisable 3,682,170 $24.61 4.83
Restricted Stock Units
The following table summarizes restricted stock unit (RSU) activities:
Number of
RSUs
Weighted Average
Grant Date Fair Value per Share
Nonvested, December 31, 202121,110 $29.61 
Granted134,460 $32.17 
Vested(21,110)$29.61 
Nonvested, September 30, 2022 (unaudited)134,460 $32.17 
There were no forfeited RSU awards during the nine months ended September 30, 2022.
Performance Share Units

The following table summarizes performance share unit (PSU) activities:

Performance-Based UnitsMarket-Based UnitsTotal PSUs
Number of PSUsWeighted
Average
Grant Date Fair Value per Share
Number of PSUsWeighted
Average
Grant Date Fair Value per Share
Number of PSUsWeighted
Average
Grant Date Fair Value per Share
Nonvested, December 31, 202153,500 $29.82 35,625 $26.34 89,125 $28.43 
Granted155,000$28.93 155,000$28.93 
Vested(22,250)$29.69 (22,250)$29.69 
Forfeited(1,500)$30.45 (1,500)$30.45 
Nonvested, September 30, 2022 (unaudited)184,750$29.08 35,625$26.34 220,375$28.64